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In vitro chemotactic responses of Brugia pahangi infective larvae to sodium ions

Published online by Cambridge University Press:  27 October 2011

Y. Mitsui*
Affiliation:
Department of Parasitology, Institute of Tropical Medicine, Nagasaki University, 1-14-2 Sakamoto, Nagasaki852-8523, Japan
M. Miura
Affiliation:
Department of Parasitology, Institute of Tropical Medicine, Nagasaki University, 1-14-2 Sakamoto, Nagasaki852-8523, Japan
D.A. Bome
Affiliation:
Kailahun Government Hospital, Kailahun District, Sierra Leone
Y. Aoki
Affiliation:
Department of Parasitology, Institute of Tropical Medicine, Nagasaki University, 1-14-2 Sakamoto, Nagasaki852-8523, Japan
*
*Fax: +81-95-819-7824 E-mail: ymitsui@nagasaki-u.ac.jp

Abstract

In vitro chemotactic responses of infective third-stage larvae (L3) of Brugia pahangi to NaCl, Na2HPO4, KCl, K2HPO4, MgCl2 and CaCl2 were assessed. Compared to deionized water as a control, 200 mm NaCl and 100 mm Na2HPO4 significantly attracted L3 (P < 0.01 and P < 0.01), whereas L3 were likely to avoid 200 mm KCl and 100 mm K2HPO4 (P < 0.05 and P < 0.05). L3 showed no significant tendency to avoid or to be attracted to 200 mm CaCl2 and 200 mm MgCl2. Furthermore, NaCl exhibited a significant chemoattractant activity for L3 at a low concentration of 100 mm.

Type
Research Papers
Copyright
Copyright © Cambridge University Press 2011

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