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Litomosoides carinii: retardation of worm growth and of migration of challenge infections in jirds (Meriones unguiculatus)

Published online by Cambridge University Press:  18 November 2009

David J. Weiner
Affiliation:
Laboratory of Parasitology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Brandon Y. Leeds
Affiliation:
Laboratory of Parasitology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA

Abstract

Inbred jirds (Meriones unguiculatus) were divided into three groups; each animal in two of the groups was infected with 30 infective larvae (L3) of Litomosoides carinii. When these infections were patent, the jirds of one of the two infected groups plus those of the third group were injected with 30 L3 L. carinii each. All animals were killed either on day 14 or 24 after the second infection for the recovery, enumeration and measurement of all worms and developing larvae. Challenge larvae were stunted (smaller) and fewer than control larvae. Additionally, fewer challenge larva were recovered on day 14 than on day 24, indicating that migration to the pleural cavity was retarded.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1985

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