Hostname: page-component-84b7d79bbc-rnpqb Total loading time: 0 Render date: 2024-07-25T08:20:15.051Z Has data issue: false hasContentIssue false
  • English
  • Français

Sexual development of Taenia solium in hamsters from rodent-derived cysticerci

Published online by Cambridge University Press:  11 April 2024

I.C. Wang ,
J.X. Guo ,
Y.X. Ma ,
W.C. Chung ,
S.C. Lu  and
P.C. Fan
I.C. Wang
Affiliation:
Institute and Department of Parasitology, National Yangming University Department of Parasitology, National Taiwan University
J.X. Guo
Affiliation:
Zhengzhou King-Shui Hospital
Y.X. Ma
Affiliation:
Henan Provincial Health and Antiendemic Station Zhengzhou, Henan, People's Republic of China
W.C. Chung
Affiliation:
Department of Parasitology Taipei Medical College, Taipei, Taiwan, Republic of China
S.C. Lu
Affiliation:
Department of Parasitology, National Taiwan University
P.C. Fan*
Affiliation:
Institute and Department of Parasitology, National Yangming University
*
*Author for correspondence. Fax: 886 2 821 4670 E-mail: pcfan@ym.edu.tw
Get access Rights & Permissions [Opens in a new window]

Abstract

In order to determine whether Taenia solium can be maintained in the laboratory using rodents as definitive hosts, six nude rats, 20 immunosuppressed Mongolian gerbils and 20 immunosuppressed Syrian hamsters were each inoculated through a stomach tube with three cysticerci recovered from SCID mice. No adult worms of T. solium were found in the intestinal tract of any of these 46 rodents. In addition, five immunosuppressed Syrian hamsters were fed with the same number of cysticerci enclosed in rodent muscles from SCID mice. Two of these hamsters were found to be infected 40 days post-infection, each harbouring a sexually developed worm in the intestinal tract. Although no eggs were produced, prepatent infections may be possible if a longer time was allowed for worm development. Moreover, the maintenance of the life cycle of T. solium in the laboratory using the rodent model can be established.

Type
Research Article
Information
Journal of Helminthology , Volume 73 , Issue 4 , April 1999 , pp. 347 - 350
Copyright
Copyright © Cambridge University Press 1999

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Allan, J.C., Garcia-Dominguez, C., Craig, P.S., Rogan, M.T., Lowe, B.S. & Flisser, A. (1991) Sexual development of Taenia solium in hamsters. Annals of Tropical Medicine and Parasitology 85, 573–576.CrossRefGoogle ScholarPubMed
Beaver, P.C., Jung, R.C. & Cupp, E.W. (1984) Clinical parasitology. 9th edn, p. 512. Lea & Febiger Co.Google Scholar
Chao, W.H. (1994) Human parasitology. 2nd edn, p. 568. Peking, People Health Printing Co. (in Chinese).Google Scholar
Gnezdilov, V.G. (1957) The golden hamster (Mesocricetus auratus Waterhouse) as a potential definitive host of the tapeworm Taenia solium . Zoologicheski Zhurnal 36, 1770–1773 (in Russian).Google Scholar
Ito, A., Chung, W.C., Chen, C.C., Ito, M., Endo, S., Okamoto, M. & Fan, P.C. (1997a) Human Taenia eggs develop into cysticerci in scid mice. Parasitology 114, 85–88.CrossRefGoogle ScholarPubMed
Ito, A., Ito, M., Eom, K.S., Chung, W.C., Chen, C.C., Ma, L., Endo, S. & Fan, P.C. (1997b) In vitro hatched oncospheres of Asian Taenia from Korea and Taiwan develop into cysticerci in the peritoneal of female scid (severe combined immunodeficiency) mice. International Journal for Parasitology 27, 631–633.CrossRefGoogle ScholarPubMed
Schmidt, G.D. & Roberts, L.S. (1989) Foundations of parasitology. 4th edn, p. 355. Times Mirror/Mosby College Publishing.Google Scholar
Stevenson, P. (1983) Observations on the hatching and activation of fresh Taenia saginata eggs. Annals of Tropical Medicine and Parasitology 77, 399–404.CrossRefGoogle ScholarPubMed
Verster, A. (1971) Preliminary report on the golden hamster as a definitive host of Taenia solium Linnaeus, 1758 and Taenia saginata Goeze, 1782. Onderstepoort Journal of Veterinary Research 38, 63–64.Google ScholarPubMed
Verster, A. (1974) The golden hamster as a definitive host of Taenia solium and Taenia saginata . Onderstepoort Journal of Veterinary Research 41, 23–28.Google ScholarPubMed
Wang, I.C. Ma, Y.X., Kuo, C.H. & Fan, P.C. (1997) A comparative study on egg hatching methods and oncospheres viability determination for Taenia solium eggs. International Journal for Parasitology 27, 1311–1314.CrossRefGoogle ScholarPubMed
Wang, I.C. Ma, Y.X., Guo, J.X., Chung, W.C., Lu, S.C., Ito, A. Fan, P.C. (1999) Oncospheres of Taenia solium and T. saginata asiatica develop into metacestodes in normal and immunosuppressed mice. Journal of Helminthology 73, in press.CrossRefGoogle Scholar
Wardle, R.A. & Mcleod, J.A. (1968) The zoology of tapeworms. p. 121. Haforer Publishing Co.Google Scholar