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Inner-ear obliteration in ulcerative colitis patients with sensorineural hearing loss

Published online by Cambridge University Press:  18 December 2007

S Kariya ,
K Fukushima ,
Y Kataoka ,
S Tominaga  and
K Nishizaki
S Kariya*
Affiliation:
Department of Otolaryngology–Head and Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Japan
K Fukushima
Affiliation:
Department of Otolaryngology–Head and Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Japan
Y Kataoka
Affiliation:
Department of Otolaryngology–Head and Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Japan
S Tominaga
Affiliation:
Department of Otolaryngology–Head and Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Japan
K Nishizaki
Affiliation:
Department of Otolaryngology–Head and Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Japan
*
Address for correspondence: Dr Shin Kariya, Department of Otolaryngology–Head and Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Okayama 700-8558, Japan. Fax: +81 86 235 7308 E-mail: skariya@cc.okayama-u.ac.jp
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Abstract

Objective:

Systemic autoimmune diseases, including ulcerative colitis, may involve the inner ear. Several ulcerative colitis cases presenting with sensorineural hearing loss have been reported. We report the T2-weighted, three-dimensional, inner-ear magnetic resonance imaging findings in the inner ears of two such patients.

Methods:

Case reports and a review of the literature concerning autoimmune disease and sensorineural hearing loss are presented.

Results:

We describe two cases of ulcerative colitis with sensorineural hearing loss in which three-dimensional magnetic resonance imaging revealed obliteration of the inner ear. Those inner ears with obliteration had severe hearing loss, and responded poorly to steroid therapy.

Conclusion:

To our knowledge, there has been no previous published report of the T2-weighted, inner-ear magnetic resonance imaging findings of cases of ulcerative colitis with sensorineural hearing loss. This paper represents the first published report in the world literature of inner-ear obliteration in such patients. Three-dimensional magnetic resonance imaging is beneficial in elucidating the pathophysiology of the inner-ear involvement seen in ulcerative colitis.

Keywords

Ulcerative ColitisSensorineural Hearing LossMRIInner Ear
Type
Clinical Record
Information
The Journal of Laryngology & Otology , Volume 122 , Issue 8 , August 2008 , pp. 871 - 874
Copyright
Copyright © JLO (1984) Limited 2007

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References

1Mathews, J, Kumar, BN. Autoimmune sensorineural hearing loss. Clin Otolaryngol Allied Sci 2003;28:479–88CrossRefGoogle ScholarPubMed
2McCabe, BF. Autoimmune sensorineural hearing loss. Ann Otol Rhinol Laryngol 1979;88:585–9CrossRefGoogle ScholarPubMed
3Moris, G, Milla, A, Ribacoba, R, Gonzalez, C. Acute deafness as an extraintestinal manifestation of ulcerative colitis. Eur J Intern Med 2005;16:440–2CrossRefGoogle ScholarPubMed
4Melhem, ER, Shakir, H, Bakthavachalam, S, MacDonald, CB, Gira, J, Caruthers, SD et al. Inner ear volumetric measurements using high-resolution 3D T2-weighted fast spin-echo MR imaging: initial experience in healthy subjects. AJNR Am J Neuroradiol 1998;19:1819–22Google ScholarPubMed
5Billings, PB, Keithley, EM, Harris, JP. Evidence linking the 68 kilodalton antigen identified in progressive sensorineural hearing loss patient sera with heat shock protein 70. Ann Otol Rhinol Laryngol 1995;104:181–8CrossRefGoogle Scholar
6Ma, C, Billings, P, Harris, JP, Keithley, EM. Characterization of an experimentally induced inner ear immune response. Laryngoscope 2000;110:451–6Google ScholarPubMed
7Hoistad, DL, Schachern, PA, Paparella, MM. Autoimmune sensorineural hearing loss: a human temporal bone study. Am J Otolaryngol 1998;19:33–9CrossRefGoogle ScholarPubMed
8Zavod, MB, Sataloff, RT, Rao, VM. Frequency of cochlear enhancement on magnetic resonance imaging in patients with autoimmune sensorineural hearing loss. Arch Otolaryngol Head Neck Surg 2000;126:969–71CrossRefGoogle ScholarPubMed
9Stillman, AE, Remley, K, Loes, DJ, Hu, X, Latchaw, RE. Steady-state free precession imaging of the inner ear. AJNR Am J Neuroradiol 1994;15:348–50Google ScholarPubMed
10Casselman, JW, Kuhweide, R, Deimling, M, Ampe, W, Dehaene, I, Meeus, L. Constructive interference in steady state-3DFT MR imaging of the inner ear and cerebellopontine angle. AJNR Am J Neuroradiol 1993;14:47–57Google ScholarPubMed
11Phelps, PD. Fast spin echo MRI in otology. J Laryngol Otol 1994;108:383–94CrossRefGoogle ScholarPubMed
12Naganawa, S, Itoh, T, Fukatsu, H, Ishigaki, T, Nakashima, T, Kassai, Y et al. Three-dimensional fast spin-echo MR of the inner ear: ultra-long echo train length and half-Fourier technique. AJNR Am J Neuroradiol 1998;19:739–41Google ScholarPubMed
13Czerny, C, Rand, T, Gstoettner, W, Woelfl, G, Imhof, H, Trattnig, S. MR imaging of the inner ear and cerebellopontine angle: comparison of three-dimensional and two-dimensional sequences. AJR Am J Roentgenol 1998;170:791–6CrossRefGoogle ScholarPubMed
14Krombach, GA, Martiny, S, Di Martino, E, Westhofen, M, Stanzel, S, Haage, P et al. T2-weighted turbo spin-echo images, maximum-intensity projections, and three-dimensional volume-rendering for delineation of pathologies and anatomic details of the inner ear. Invest Radiol 1998;39:756–66CrossRefGoogle Scholar
15Lane, JI, Ward, H, Witte, RJ, Bernstein, MA, Driscoll, CL. 3-T imaging of the cochlear nerve and labyrinth in cochlear-implant candidates: 3D fast recovery fast spin-echo versus 3D constructive interference in the steady state techniques. AJNR Am J Neuroradiol 2004;25:618–22Google ScholarPubMed
16Ruckenstein, MJ. Autoimmune inner ear disease. Curr Opin Otolaryngol Head Neck Surg 2004;12:426–30CrossRefGoogle ScholarPubMed
17Harris, JP, Weisman, MH, Derebery, JM, Espeland, MA, Gantz, BJ, Gulya, AJ et al. Treatment of corticosteroid-responsive autoimmune inner ear disease with methotrexate: a randomized controlled trial. JAMA 2003;290:1875–83CrossRefGoogle ScholarPubMed
18Dowd, A, Rees, WD. Treatment of sensorineural deafness associated with ulcerative colitis. Br Med J (Clin Res Ed) 1987;295:26CrossRefGoogle ScholarPubMed
19Kumar, BN, Walsh, RM, Wilson, PS, Carlin, WV. Sensorineural hearing loss and ulcerative colitis. J Laryngol Otol 1997;111:277–8CrossRefGoogle ScholarPubMed