Hostname: page-component-84b7d79bbc-fnpn6 Total loading time: 0 Render date: 2024-07-29T09:38:48.397Z Has data issue: false hasContentIssue false
  • English
  • Français

The migration theory of cholesteatoma formation. Some experimental observations

Published online by Cambridge University Press:  29 June 2007

Gerard M. O'Donoghue
Gerard M. O'Donoghue*
Affiliation:
London
*
G. M. O'Donoghue, Ch. M., F.R.C.S., F.R.C.S.I., Department of Otolaryngology, The Radelife Infirmary, Oxford. OX2 6HE.
Get access Rights & Permissions [Opens in a new window]

Abstract

The migration theory of cholesteatoma formation considers that stratified squamous epithelium from the external auditory meatus migrates into the middle ear, giving rise to cholesteatoma. To test the ability of squamous epithelium to migrate in this manner, 73 stains were placed in relation to 23 chronic perforations. In no instance did epithelium migrate into the middle ear cleft. The limitations of the migration theory are discussed.

Type
Research Article
Information
The Journal of Laryngology & Otology , Volume 100 , Issue 4 , April 1986 , pp. 395 - 398
Copyright
Copyright © JLO (1984) Limited 1986

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Bezold, F. (1890) Cholesteatom, Perforation der Membrana flaccida Shrapnelli, und Tubenverschluss. Zeitschrift für Ohrenheilkunde, 20: 5–9.Google Scholar
Buckingham, R. A. and Ferrer, L. J. (1973) Middle Ear pressures in Eustachian tube malfunction: manometric studies. Laryngoscope, 83: 1585–1593.CrossRefGoogle ScholarPubMed
Cawthorne, T. (1963) Congenital Cholesteatoma. Archives of Otolaryngology, 78: 248–252.CrossRefGoogle ScholarPubMed
Cruveillier, L. J. B. (1829) Anatomie pathologique du Corps humain. Livre 1–20. Ballière. Paris.Google Scholar
Habermann, J. (1888) Zur Entstehung des Cholesteatoms des Mittelohrs. (Cysten in der Schleimhaut der Paukenhohle. Atrophie der nerven in der Schnecke). Archiv für Ohrenheilkunde, 27: 42–46.CrossRefGoogle Scholar
Lim, D. J. (1968) Tympanic Membrane: Part II, Pars Flaccida. Acta Otolaryngologica (Stockholm). 66: 515–532.CrossRefGoogle Scholar
Sadé, J. (1978) Pathogenesis of Attic Cholesteatomas. Journal of the Royal Society of Medicine, 71: 716–732.CrossRefGoogle ScholarPubMed
Sadé, J. (1979) Secretory Otitis Media and its sequelae. Churchill Livingstone. New York.Google Scholar
Sadé, J. (1982) Cholesteatoma and Mastoid Surgery: Proceedings 2nd International Conference (1982). Ed. Sadé, J., Kugler PublicAmsterdam.Google Scholar
Simmons, F. B. (1961) Epithelial migration in central type tympanic perforations. Preliminary report on a potential diagnostic tool. Archives of Otolaryngology, 74: 435–437.CrossRefGoogle ScholarPubMed
Tomasetti, L. (1965) Osservazioni Sulla Migrazion dell 'epitelio della Membrana timpanica in timpani peforati. Bullettino O.G.N., 83: 805–821.Google Scholar