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Spindle cell carcinoma of the parotid gland

Published online by Cambridge University Press:  29 June 2007

Toshio Ishibashi  and
Hiroshi Hojo
Toshio Ishibashi*
Affiliation:
Department of Otolaryngology, Kanto Teishin Hospital, Tokyo, Japan.
Hiroshi Hojo
Affiliation:
Department of Pathology, Fukushima Medical College, Fukushima, Japan.
*
Dr Toshio Ishibashi, Department of Otolaryngology, Kanto Teishin Hospital, 5-9-22, Higashi-Gotanda, Shinagawa-ku, Tokyo 141, Japan. Fax: 3-3448-6617
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Abstract

Spindle cell carcinomas of the salivary gland are extremely rare, with only a few cases having been previously reported. We present a 55-year-old man with a rapidly enlarging mass in the left parotid gland. Despite radical surgery, the tumour recurred, and led to death 11 months later. Histopathologically, the tumour was composed of two components, a squamous cell carcinoma component and a spindle cell sarcomatoid component. A diagnosis of primary spindle cell carcinoma of the parotid gland was made. Immunohistochemical studies revealed keratin positivity and vimentin negativity in the squamous cell carcinoma component: the spindle cell sarcomatoid component was positive for vimentin and negative for keratin, but showed focal positivity for epithelial membrane antigen. The origin of the sarcomatoid component and the differential diagnosis from malignant mixed tumours are discussed.

Keywords

Salivary gland neoplasmsParotid glandCarcinomaspindle cellImmunohistochemistry
Type
Pathology in Focus
Information
The Journal of Laryngology & Otology , Volume 109 , Issue 7 , July 1995 , pp. 683 - 686
Copyright
Copyright © JLO (1984) Limited 1995

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