Hostname: page-component-5c6d5d7d68-pkt8n Total loading time: 0 Render date: 2024-08-15T15:21:10.911Z Has data issue: false hasContentIssue false
  • English
  • Français

Tinnitus as the presenting symptom in a case of Lhermitte-Duclos disease

Published online by Cambridge University Press:  29 June 2007

C. J. Lobo ,
R. Mehan ,
E. Murugasu  and
R. D. Laitt
C. J. Lobo
Affiliation:
University Department of Otolaryngology, Manchester Royal Infirmary, Manchester, UK.
R. Mehan
Affiliation:
University Department of Neuroradiology, Manchester Royal Infirmary, Manchester, UK.
E. Murugasu
Affiliation:
University Department of Otolaryngology, Manchester Royal Infirmary, Manchester, UK.
R. D. Laitt*
Affiliation:
University Department of Neuroradiology, Manchester Royal Infirmary, Manchester, UK.
*
Address for correspondence: Dr. R. D. Laitt, Consultant Neuroradiologist, Department of Neuroradiology, Manchester Royal Infirmary, Oxford Road, Manchester M13 9WL.
Get access Rights & Permissions [Opens in a new window]

Abstract

Dysplastic gangliocytoma or Lhermitte-Duclos disease (LDD) is a hamartomatous malformation of the cerebellar hemisphere that usually presents with signs of increased intracranial pressure or symptoms of cerebellar dysfunction. In this paper, we report a case of LDD presenting with tinnitus, and postulate a probable mechanism for this unusual presentation.

Keywords

Cerebellar diseasesTinnitis
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 113 , Issue 5 , May 1999 , pp. 464 - 465
Copyright
Copyright © JLO (1984) Limited 1999

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Ahmmed, A. U., Mackenzie, I., Das, V. K., Chaterjee, S., Lye, R. H. (1996) Audio-vestibular manifestations of Chiari malformation and outcome of surgical decompression: A case report. Journal of Laryngology and Otology 110: 1060–1064.CrossRefGoogle ScholarPubMed
Herzog, J. A., Bailey, S., Meyer, J. (1997) Vascular loops of the internal auditory canal: A diagnostic dilemma. American Journal of Otology 18: 26–31.Google Scholar
Kulkantrakorn, K., Awwad, E. E., Levy, B., Selhorst, J. B., Cole, H. O., Leake, D., Gussler, J. R., Epstein, A. D., Malik, M. M. (1997) MRI in Lhermitte-Duclos disease. Neurology 48: 725–731.CrossRefGoogle ScholarPubMed
Lhermitte, J., Duclos, P. (1920) Sur un ganglioneuroma diffus du cortex du cervelet. Bulletin de l'Association Francais Ais Etude pour du Cancer (Paris) 9: 99–107.Google Scholar
Liaw, D., Marsh, D. J., Li, J., Dahia, P. L., Wang, S. I., Zheng, Z., Bose, S., Call, K. M., Tsou, H. C., Peacocke, M., Eng, C., Parasons, R. (1997) Germline mutatitons of the PTEN gene in Cowden's disease, an inherited breast and thyroid cancer syndrome. Nature Genetics 16: 64–67.CrossRefGoogle ScholarPubMed
Milbouw, G., Born, J. D., Martin, D., Collignon, J., Hans, P., Reznik, M., Bonnal, J. (1988) Clinical and radiological aspects of dysplastic gangliocytoma (Lhermitte-Duclos disease): A case report of two cases with review of literature. Neurosurgery 22: 124–128.Google Scholar
Morgan, D., Williams, B. (1992) Syringobulbia: a surgical appraisal. Journal of Neurology, Neurosurgery and Psychiatry 55: 1132–1141.Google Scholar
Reznick, M., Schoenen, J. (1983) Lhermitte-Duclos disease. Acta Neuropathologica 59: 88–94.CrossRefGoogle Scholar
Roski, R. A., Roessmann, U., Spetzler, R. F., Kaufman, B., Nulsen, F. E. (1981) Clinical and pathological study of dysplastic gangliocytoma. Journal of Neurosurgery 55: 318–321.Google Scholar
Vinchon, M., Blond, S., Lojeune, J. P., Krivosik, I., Fossati, P., Assaker, R., Christiaens, J. L. (1994) Association of Lhermitte-Duclos and Cowden's disease: report of a new case and review of the literature. Journal of Neurology, Neurosurgery, and Psychiatry 57: 699–704.CrossRefGoogle ScholarPubMed
Wells, G. B., Lasner, T. M., Yousem, D. M., Zagler, E. L. (1994) Lhermitte-Duclos disease and Cowden's syndrome in an adolescent patient. Journal of Neurosurgery 81: 133–136.CrossRefGoogle Scholar