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Chlorine-induced anosmia. A case presentation

Published online by Cambridge University Press:  29 June 2007

E. Benjamin  and
J. Pickles
E. Benjamin
Affiliation:
Department of ENT Surgery, Luton and Dunstable Hospital, Luton, UK
J. Pickles*
Affiliation:
Department of ENT Surgery, Luton and Dunstable Hospital, Luton, UK
*
Address for correspondence: Mr J. Pickles, ENT Department, Luton and Dunstable Hospital, Lewsey Road, Luton LU4 0DZ
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Abstract

Chlorine gas is known to be a potent irritant to the eyes, nose, throat and lungs with severe exposure resulting in pulmonary oedema and even death. There have been no case reports, however, of chlorine inducing anosmia. We present such a case, along with a review of the literature on the toxicology of chlorine and its effect on the nose.

Keywords

ChlorineAnosmiaSmell
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 111 , Issue 11 , November 1997 , pp. 1075 - 1076
Copyright
Copyright © JLO (1984) Limited 1997

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References

Hansen, D. (1970) Occupationally induced anosmia due to chronic carbon monoxide effect. HNO 18(5): 140–142.Google ScholarPubMed
Harada, N., Dodo, H., Fujii, M. (1983) Olfactory disorders in chemical plant workers exposed to SO2 and or NH3 Japanese Journal of Industrial Health 25(1): 28–29.Google ScholarPubMed
Henkin, R. I. (1982) Olfaction in human disease. In Otolaryngology. Volume 2 (English, G. M., ed.), Harper and Row, New York, pp. 1–37.Google Scholar
Jiang, X. Z., Buckley, L. A., Morgan, K. T. (1983) Pathology of toxic responses to the RD50 concentration of chlorine gas in the nasal passages of rats and mice. Toxicology and Applied Pharmacology 71: 225–236.CrossRefGoogle Scholar
Latkowski, B., Zalewski, P., Najwer, K., Zbrzeny, K., Czyzewski, I. (1981) Evaluation of the senses of taste and smell in petroleum chemistry workers based on 3 year observations. Medycyna Pracy 32(1): 51–57.Google ScholarPubMed
McNulty, M. J., Chang, J. C. F., Barrow, C. S., Casanova-Shmitz, M., Heck, H. d'A. (1983) Sulfhydryl oxidation in rat nasal mucosal tissue after chlorine inhalation. Toxicology Letters 17: 241–246.CrossRefGoogle ScholarPubMed
National Poisons Information Service (1997) Chlorine. Medical Toxicology Unit, Guy's Hospital, London.Google Scholar
Occupational Exposure Limits. Criteria Document Summaries (1993) Health and Safety Executive. Her Majesty's Stationery Office, London.Google Scholar
Owen, W. (1921) In Poems by Wilfred Owen with an introduction by Siegfried Sassoon. Chatton and Windus, London.Google Scholar
Ramachandran, K. A., Chawla, I. S., Khokhor, P. (1990) Acute chlorine poisoning. A study of 84 cases. Journal of the Association of Physicians of India 38: 489–490.Google ScholarPubMed
Rose, C. S., Heywood, P. G., Costanzo, R. M. (1992) Olfactory impairment after chronic occupational cadmium exposure. Journal of Occupational Medicine 34(6): 600–605.Google ScholarPubMed
Sandall, T. E. (1922) The later effects of gas poisoning. Lancet 2: 857–859.CrossRefGoogle Scholar
Schwartz, D. A., Smith, D. D., Lakshminarayan, S. (1990) The pulmonary sequelae associated with accidental inhalation of chlorine gas. Chest 97: 820–825.CrossRefGoogle ScholarPubMed
Shroff, C. P., Khade, M. V., Svinivasan, M. (1988) Respiratory cytopathology in chlorine gas toxicity. A study in 28 subjects. Diagnostic Cytopathology 4: 28–32.CrossRefGoogle ScholarPubMed
Small, M., Murray, J. A. (1987) Nasal changes following immersion in chlorinated water. Rhinology 25(3): 153–157.Google ScholarPubMed
Trevethick, R. A. (1980) Environmental and Industrial Health Hazards, a Practical Guide, 2nd Edition. Heinmann, London. 52.Google Scholar
Watanabe, S., Fukuchi, Y. (1981) Occupational impairment of the olfactory sense of chromate producing workers. Japanese Journal of Industrial Health 23(6): 606–611.Google ScholarPubMed
Wolf, D. C., Morgan, K. T., Gross, E. A., Barrow, C., Moss, R. A., Popp, J. A. (1995) Two year inhalation exposure of female and male B6C3fl mice and F344 rats to chlorine gas induces lesions confined to the nose. Fundamental and Applied Toxicology 24: 111–131.CrossRefGoogle Scholar