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Parapharyngeal malignant ectomesenchymoma: Combined malignant fibrous histiocytoma and primitive neuroectodermal tumour with neuroglial differentiation

Published online by Cambridge University Press:  29 June 2007

V. Kasantikul ,
S. Shuangshoti ,
A. Cutchavaree  and
P. Bunyaphiphat
V. Kasantikul
Affiliation:
Department of Pathology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. Recipients of funds from the Anandhamahidol Foundation, Medical Section, Bangkok.
S. Shuangshoti*
Affiliation:
Department of Pathology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. Recipients of funds from the Anandhamahidol Foundation, Medical Section, Bangkok.
A. Cutchavaree
Affiliation:
Department of Ear, Nose and Throat, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
P. Bunyaphiphat
Affiliation:
Department of Ear, Nose and Throat, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
*
Professor Samruay Shuangshoti, M.D., Department of Pathology, Chulalongkorn Hospital, Bangkok 10500, Thailand.
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Abstract

A parapharyngeal ectomesenchymoma consisting of mixed malignant fibrous histiocytoma and primitive neuroectodermal tumour with neuroglial differentiation occurred in a 36-year-old woman. Immunohistochemical and electron microscopic studies verified the combined mesenchymal and neuroectodermal components within the tumour. Only 9 similar cases, including the present one, are on record. The patients ranged in age from 6 months to 49 years, with an average age of 18 years. The male: female ratio was 4:5. The tumour location was widespread. All reported ectomesenchymomas were histopathologically malignant. Recurrence and/or metastasis was/were common. The neural crest has been suggested as the origin of the ectomesenchymomas.

Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 101 , Issue 5 , May 1987 , pp. 508 - 515
Copyright
Copyright © JLO (1984) Limited 1987

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