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Patient perception of a randomised, controlled trial of laryngeal reinnervation versus thyroplasty for unilateral vocal fold paralysis

Published online by Cambridge University Press:  08 July 2015

M Mat Baki ,
R Yu ,
J S Rubin ,
E Chevretton ,
G Sandhu  and
M A Birchall
M Mat Baki
Affiliation:
Ear Institute, University College London, UK Royal National Throat, Nose and Ear Hospital, University College London Hospital NHS Trust, UK Faculty of Medicine, Universiti Kebangsaan Malaysia, Bangi, Malaysia
R Yu
Affiliation:
Joint Research Office, University College London, UK
J S Rubin
Affiliation:
Royal National Throat, Nose and Ear Hospital, University College London Hospital NHS Trust, UK
E Chevretton
Affiliation:
Guy's and St Thomas' NHS Trust, London, UK
G Sandhu
Affiliation:
Charing Cross Hospital, Imperial College Healthcare NHS Trust, London, UK
M A Birchall*
Affiliation:
Ear Institute, University College London, UK Royal National Throat, Nose and Ear Hospital, University College London Hospital NHS Trust, UK Department of Otolaryngology, University of California, Davis, USA
*
Address for correspondence: Dr Martin Anthony Birchall, Professorial Unit, Royal National Throat, Nose and Ear Hospital, 330 Grays Inn Road, London WC1X 8DA, UK E-mail: m.birchall@ucl.ac.uk
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Abstract

Objectives:

To explore unilateral vocal fold paralysis patients' perception of a proposed randomised, controlled trial of laryngeal reinnervation versus thyroplasty, and to identify patients' concerns regarding their voice.

Methods:

Seventeen patients from five voice clinics in London were identified as being eligible for the randomised, controlled trial. Eleven of these patients (9 females and 2 males; age range, 18–65 years) were interviewed using a semi-structured topic guide (they were given a minimum of 2 weeks to read through the study information sheet). The interviews were recorded, transcribed and analysed using thematic analysis.

Results:

The patients were satisfied with the clarity of the information sheet. Most of them perceived that reinnervation was a more ‘attractive’ option than thyroplasty. This may have been the result of certain phraseology used in the information sheet and by recruiters. Patients' main concern was reduced voice strength and the effects of this on work and social life.

Conclusion:

Phraseology that needed changing was identified; these changes may optimise the recruitment process for a trial. We propose using the voice handicap index 10 as the primary measure of outcome in the proposed randomised, controlled trial.

Keywords

Randomized Controlled TrialLaryngeal ReinnervationLaryngeal Nerve InjuriesThyroplastyVocal Cord Paralysis
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 129 , Issue 7 , July 2015 , pp. 693 - 701
Copyright
Copyright © JLO (1984) Limited 2015 

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