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Voice outcome after vocal fold injection augmentation with carboxymethyl cellulose versus calcium hydroxyapatite

Published online by Cambridge University Press:  04 March 2020

J T Cohen  and
L Benyamini
J T Cohen*
Affiliation:
Department of Otolaryngology Head and Neck Surgery, Rambam Healthcare Campus, The Technion, Institude of Thechnology, Haifa, Israel
L Benyamini
Affiliation:
Department of Otolaryngology Head and Neck Surgery, Rambam Healthcare Campus, The Technion, Institude of Thechnology, Haifa, Israel
*
Author for correspondence: Dr Jacob T Cohen, Department of Otolaryngology Head and Neck Surgery, Rambam Healthcare Campus, The Technion, Institude of Thechnology, Haifa, Israel E-mail: ja_cohen@rambam.health.gov.il Fax: +972 4777 2772
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Abstract

Background

Vocal fold injection augmentation is a recognised treatment modality for glottic insufficiency. Causes of glottal closure insufficiency include vocal fold paralysis, paresis, atrophy, sulcus vocalis, scarring and vocal fold deficiency after laryngeal surgery. A variety of materials exist for injection augmentation. This study aimed to compare voice improvement after injection augmentation between two injectable materials: carboxymethyl cellulose and calcium hydroxyapatite.

Method

This retrospective study included 66 consecutive patients with glottic insufficiency who underwent injection augmentation.

Results

Among the patients who received their first injection augmentation with carboxymethyl cellulose and their second injection augmentation with calcium hydroxyapatite (n = 28), voice quality improved significantly after both injection augmentations. No significant differences were observed in any of the objective and subjective voice quality measurements examined following carboxymethyl cellulose and calcium hydroxyapatite injections.

Conclusion

Voice improvement after injection augmentation depends mainly on the improvement of glottic closure, rather than the injection material.

Keywords

Vocal Cord ParalysisInjectionsGlottisHoarseness
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 134 , Issue 3 , March 2020 , pp. 263 - 269
Copyright
Copyright © JLO (1984) Limited, 2020

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Footnotes

Dr J T Cohen takes responsibility for the integrity of the content of the paper

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