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Some Pathological Changes met with in the great Nerve Cells of the Insane, with Special Reference to the condition known as “Reaction at a Distance.”

Published online by Cambridge University Press:  19 February 2018

John Turner*
Affiliation:
Read at the Annual Meeting, July 27th, 1900, and illustrated by lantern slides

Extract

The pictures I am going to show are taken from photomicrographs of the giant pyramidal nerve-cells of the upper part of the ascending frontal convolution, and the neighbouring paracentral, and my remarks refer entirely to this variety of cell. They have been studied in sections, stained after modifications of Nissl's method, and in film preparations in which the entire cell is seen.

Type
Part I.—Original Articles
Copyright
Copyright © Royal College of Psychiatrists, 1900 

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References

(1) Note.—In some cases, as e.g. in one mentioned in Brain (Winter No., 1899), degenerated nerve-fibres are found in the white matter immediately adjacent to cortex,—a figure is given showing these. Google Scholar

(2) Dr. Mott has recently in his ‘Croonian Lectures’ shown that the neuroglobulin of the nerve-cells will, on prolonged heating, coagulate between 107·6° and 109·4° F. He supposes that under these conditions there is a diffusion of the nuclei proteid into the achromatic substance of the cell, which coagulates and causes its death. This does not, however, exclude the possibility of other agencies besides heat, bringing about a diffusion and coagulation of the neuroglobulin, and resulting in a similar condition of the cell.Google Scholar

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