You will, I am sure, share my regret that this lecture is being given out of turn. It had been arranged that my lecture should follow that of Prof. Mapother, whose untimely death robbed psychiatry of a notable figure and the Association of a lecture, possibly provocative and certainly stimulating, which promised to be a memorable addition to the series. I sadly miss, too, my old friend and colleague, Sir Hubert Bond, ever the kindliest and most charitable of critics.