Hostname: page-component-5c6d5d7d68-wtssw Total loading time: 0 Render date: 2024-08-15T02:21:12.688Z Has data issue: false hasContentIssue false

Indicanuria and the Psychosis of a Pellagrin

Published online by Cambridge University Press:  08 February 2018

R. Rodnight
Affiliation:
Department of Biochemistry, Institute of Psychiatry (British Postgraduate Medical Federation, University of London) Maudsley Hospital
H. Mcilwain
Affiliation:
Department of Biochemistry, Institute of Psychiatry (British Postgraduate Medical Federation, University of London) Maudsley Hospital

Extract

Pellagra with marked mental symptoms in a boy of 10, was cured by nicotinamide (Hersov, 1955). The boy's diet prior to development of the pellagra did not however appear to have been deficient in nicotinic acid derivatives. The following studies were initiated in search for a metabolic peculiarity which might explain this.

Type
Original Articles
Copyright
Copyright © Royal College of Psychiatrists, 1955 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Beckh, W., Ellinger, P., and Spies, T. D., Quart. J. Med., 1937, 30, 305.Google Scholar
Bodansky, M., and Bodansky, O., The Biochemistry of Disease, 1952. New York: Macmillan.Google Scholar
Bouchard, C., Lectures on Autointoxication in Disease, 1894. Trans. Oliver, T. Philadelphia: Davis.Google Scholar
Caldwell, W. A., and Hardwick, S. W., J. Ment. Sci., 1944, 90, 95.CrossRefGoogle Scholar
Duncan, G. G., Diseases of Metabolism, 1947. Saunders.Google Scholar
Ellinger, P., and Coulson, R. A., Biochem. J., 1944, 38, 265.CrossRefGoogle Scholar
Folin, O., Amer. J. Insanity., 1904, 61, 299.Google Scholar
Friedemann, T. E., and Frazier, E. I., Arch. Biochem., 1950, 26, 361.Google Scholar
Goldsmith, G. A., Proc. Soc. exp. Biol., N. Y., 1942, 51, 42.CrossRefGoogle Scholar
Hersov, L., J. Ment. Sci., 1955, 101, 878.CrossRefGoogle Scholar
Herter, C. A., and Kendall, H., J. biol. Chem., 1909, 7, 203.CrossRefGoogle Scholar
Huff, J. W., and Perlzweig, W. A., J. biol. Chem., 1947, 167, 157.CrossRefGoogle Scholar
Johnson, B. C., Hamilton, T. S., and Mitchell, H. H., J. biol. Chem., 1945, 159, 231.CrossRefGoogle Scholar
Justin-Besançon, L., and Lwoff, A., Vitamine Anti-Pellagreuse et Avitaminoses Nicotiniques, 1942. Paris: Masson.Google Scholar
Leigh, D., J. Ment. Sci., 1952, 98, 130.CrossRefGoogle Scholar
Medical Research Council, Vitamins, 1932. London: H.M.S.O. Google Scholar
Reiter, P. J., and Jacobsen, J., Pellagroide Dermatosen an Geistekranken., 1935. Kopenhagen: Levin and Munksgaard.Google Scholar
Segal, L., J. metab. Res., 1924, 5, 293.Google Scholar
Sharlit, H., J. biol. Chem., 1932, 99, 537.CrossRefGoogle Scholar
Townsend, A. D., J. Ment. Sci., 1905, 51, 51.CrossRefGoogle Scholar
Watson, C. J., Proc. Soc. exp. Biol., N. Y., 1939, 41, 591.CrossRefGoogle Scholar
Williams, R. J., Eakin, R. E., Beerstecher, E., and Shive, W., Biochemistry of the B Vitamins, 1950. New York: Reinhold.CrossRefGoogle Scholar
Wooldridge, W. E., Mast, G. W., and Hoffman, M., J. Lab. clin. Med., 36, 501.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.