Hostname: page-component-848d4c4894-xfwgj Total loading time: 0 Render date: 2024-07-02T15:27:20.471Z Has data issue: false hasContentIssue false
  • English
  • Français

Fabrication of anthropomorphic phantoms for use in total body irradiations studies

Published online by Cambridge University Press:  07 October 2019

Shaghayegh F. Monzari ,
Ghazale Geraily Open the ORCID record for Ghazale Geraily [Opens in a new window] ,
Tahereh Hadisi nia ,
Soraya Salmanian ,
Heydar Toolee  and
Mostafa Farzin
Shaghayegh F. Monzari
Affiliation:
Medical Physics Department, Tehran University of Medical Science, Tehran, Iran
Ghazale Geraily*
Affiliation:
Medical Physics Department, Tehran University of Medical Science, Tehran, Iran Cancer Institute of Imam Khomeini Hospital, Tehran University of Medical Science, Tehran, Iran
Tahereh Hadisi nia
Affiliation:
Medical Physics Department, Tehran University of Medical Science, Tehran, Iran
Soraya Salmanian
Affiliation:
Radiation Oncology Department, Iran University of Medical Science, Iran Gamma Knife Center, Tehran, Iran
Heydar Toolee
Affiliation:
Anatomy Department, Tehran University of Medical Science, Tehran, Iran
Mostafa Farzin
Affiliation:
Cancer Institute of Imam Khomeini Hospital, Tehran University of Medical Science, Tehran, Iran
*
Author for Correspondence: Ghazale Geraily, Medical Physics Department, Iran Gamma Knife Center, Tehran University of Medical Science, Tehran, Iran. Tel: +989124308726. E-mail: ghazalegraily@yahoo.com
Get access Rights & Permissions [Opens in a new window]

Abstract

Purpose:

The aim of this study was to produce a low-cost anatomical model of adult male including lower limbs to evaluate the three-dimensional dose distribution for dosimetry measurements, especially in total body irradiation (TBI) and total skin electron therapy (TSET).

Materials and methods:

Computed tomography (CT) scan images of the atomic energy organisation RANDO phantom and lower limb CT scan images of 20 healthy persons were averaged. Selections of different body tissues substitute materials and phantom validation were performed according to previous studies worked on construction of radiation therapy phantoms.

Results:

The dosimetry aspect of the selected substitute materials from all considered methods showed that they were in good agreement with real human tissue, especially bone, with a percentage error of 0·5%. The results show that the electron densities obtained from the linear attenuation coefficient (reDLAC) for the tissue equivalent material used in the phantom is a better option for validation.

Conclusions:

This validated phantom has numerous advantages over the origin type of RANDO phantom. Therefore, using it in TBI and TSET dosimetry is recommendable.

Keywords

dosimetryRANDO phantomTBITSET
Type
Original Article
Information
Journal of Radiotherapy in Practice , Volume 19 , Issue 3 , September 2020 , pp. 242 - 247
Copyright
© Cambridge University Press 2019

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Parida, DK, Verma, KK, Chander, S, Joshi, R, Rath, GK.Total skin electron irradiation therapy in mycosis fungoides using high-dose rate mode: a preliminary experience. Int J Dermatol 2005; 44 (10): 828–830.10.1111/j.1365-4632.2005.02217.xCrossRefGoogle ScholarPubMed
Chen, Z, Agostinelli, AG, Wilson, LD, Nath, R.Matching the dosimetry characteristics of a dual-field Stanford technique to a customized single-field Stanford technique for total skin electron therapy. Int J Radiat Oncol Biol Phys 2004; 59 (3): 872–885.10.1016/j.ijrobp.2004.02.046CrossRefGoogle ScholarPubMed
Diamandidou, E, Cohen, PR, Kurzrock, R.Mycosis fungoides and Sezary syndrome [see comments]. Blood 1996; 88 (7): 2385–2409.CrossRefGoogle Scholar
Le Bourgeois, J, Bridier, A, Bounik, H, Schlienger, M.Whole cutaneous irradiation in mycosis fungoides with 55KV x-rays. Technical study. Bull Cancer 1977; 64 (2): 313–322.Google ScholarPubMed
Lučić, F, Sánchez-Nieto, B, Caprile, P, Zelada, G, Goset, K.Dosimetric characterization and optimization of a customized Stanford Total Skin Electron Irradiation (TSEI) technique. J Appl Clin Med Phys 2013; 14 (5): 1–12.10.1120/jacmp.v14i5.4388CrossRefGoogle ScholarPubMed
Wood, NK, Goaz, P, Jacobs, M.Multiple Separate, Well-Defined Radiolucencies. Differential Diagnosis of Oral and Maxillofacial Lesions, 5th edition. St Louis, MO: Mosby-Year Book, Inc., 1997: 387–389.Google Scholar
Henig, I, Zuckerman, T.Hematopoietic stem cell transplantation—50 years of evolution and future perspectives. Rambam Maimonides Med J 2014; 5 (4): e0028.10.5041/RMMJ.10162CrossRefGoogle ScholarPubMed
Khan, FMThe Physics of Radiation Therapy. Philadelphia, PA: Lippincott Williams & Wilkins, 2014: P 135–P 136.Google Scholar
Goldstone, K.Book Review-Tissue substitutes in radiation dosimetry and measurement, in: ICRU Report 44. International Commission on Radiation Units and Measurements, USA (1989). Clin Radiol 1990; 41 (3): 220–221.CrossRefGoogle Scholar
Winslow, JF, Hyer, DE, Fisher, RF, Tien, CJ, Hintenlang, DE.Construction of anthropomorphic phantoms for use in dosimetry studies. J Appl Clin Med Phys 2009; 10 (3): 195–204.CrossRefGoogle ScholarPubMed
Goldstone, K.Tissue substitutes in radiation dosimetry and measurement. In: ICRU Report 44, International Commission on Radiation Units and Measurements, USA (1989). Bethesda, MD: WB Saunders, 1990; 188–190.Google Scholar
White, D, Martin, R, Darlison, R.Epoxy resin based tissue substitutes. Br J Radiol 1977; 50 (599): 814–821.CrossRefGoogle ScholarPubMed
Behmadi, M, Gholamhosseinian, H, Mohammadi, M, Naseri, S, Momennezhad, M, Bayani, Set al. Evaluation of breast cancer radiation therapy techniques in outfield organs of Rando phantom with thermoluminescence dosimeter. J Biomed Phys Eng 2019; 9 (2): 179–188.Google ScholarPubMed
Falahati, L, Nedaie, HA, Esfahani, M, Banaee, N.Dosimetric evaluation of electron total skin irradiation using gafchromic film and thermoluminescent dosimetry. J Cancer Res Ther 2019; 15 (8): 115–122.Google ScholarPubMed
Santos, FS, Gomez, AML, da Silva, CAM, do Carmo Santana, P, Mourao, AP. Analysis of thyroid absorbed dose in cervical CT scan with the use of bismuth shielding. Braz J Radiat Sci 2019; 7 (2A): 1–8.Google Scholar
Archer, BR, Glaze, S, North, LB, Bushong, SC.Dosimeter placement in the Rando phantom. Med Phys 1977; 4 (4): 315–318.10.1118/1.594320CrossRefGoogle ScholarPubMed
DeWerd, LA, Kissick, M.The Phantoms of Medical and Health Physics. Berlin: Springer, 2014: 41–43.10.1007/978-1-4614-8304-5CrossRefGoogle Scholar
Allahverdi, M, Geraily, G, Esfehani, M, Sharafi, A, Haddad, P, Shirazi, A.Dosimetry and verification of 60Co total body irradiation with human phantom and semiconductor diodes. J Med Phys/Assoc Med Physicists India 2007; 32 (4): 169–174.Google Scholar
Kucuk, N, Cakir, M, Isitman, NA.Mass attenuation coefficients, effective atomic numbers and effective electron densities for some polymers. Radiat Prot Dosimetry 2012; 153 (1): 127–34.CrossRefGoogle ScholarPubMed
Valentin, J.Basic anatomical and physiological data for use in radiological protection: reference values: ICRP Publication 89. Annals of the ICRP 2002; 32 (3–4): 1–277.CrossRefGoogle Scholar