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Observations on the Pathophysiology and Mechanisms for Cyclic Neutropenia

Published online by Cambridge University Press:  15 May 2008

C. Colijn ,
D. C. Dale ,
C. Foley  and
M. C. Mackey
C. Colijn
Affiliation:
Department of Engineering Mathematics, University of Bristol, Bristol, UK, BS8 1TR
D. C. Dale
Affiliation:
Department of Medicine, University of Washington, Seattle, Washington, USA, 98195
C. Foley
Affiliation:
Department of Mathematics and Centre for Nonlinear Dynamics, McGill University 3655 Promenade Sir William Osler, Montreal, QC, Canada, H3G 1Y6
M. C. Mackey*
Affiliation:
Department of Mathematics and Centre for Nonlinear Dynamics, McGill University 3655 Promenade Sir William Osler, Montreal, QC, Canada, H3G 1Y6
*
michael.mackey@mcgill.ca
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Abstract

We review the basic pathology of cyclical neutropenia in both humans and the grey collie, and examine the role that mathematical modeling of hematopoietic cell production has played in our understanding of the origins of this fascinating dynamical disease.

Keywords

cyclic neutropenia
Type
Research Article
Information
Mathematical Modelling of Natural Phenomena , Volume 1 , Issue 2: Hematopoiesis and blood diseases , 2006 , pp. 45 - 69
Copyright
© EDP Sciences, 2006

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