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High Resolution Imaging of Virus in Liquid Droplets: The Application of Cryo-TEM Methodology to Improve Liquid-phase TEM Imaging of Biological Materials

Published online by Cambridge University Press:  03 December 2021

Madeline J. Dukes ,
GM Jonaid ,
William J. Dearnaley ,
Michael A. Casasanta  and
Deborah F. Kelly
Madeline J. Dukes
Affiliation:
Protochips, Inc.Morrisville, NC, USA.
GM Jonaid
Affiliation:
Bioinformatics and Genomics Graduate Program, Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, PA, USA. Department of Biomedical Engineering, Pennsylvania State University, University Park, PA, USA. Materials Research Institute, Pennsylvania State University, University Park, PA, USA. Center for Structural Oncology, Pennsylvania State University, University Park, PA16802, USA.
William J. Dearnaley
Affiliation:
Department of Biomedical Engineering, Pennsylvania State University, University Park, PA, USA. Materials Research Institute, Pennsylvania State University, University Park, PA, USA. Center for Structural Oncology, Pennsylvania State University, University Park, PA16802, USA.
Michael A. Casasanta
Affiliation:
Department of Biomedical Engineering, Pennsylvania State University, University Park, PA, USA. Materials Research Institute, Pennsylvania State University, University Park, PA, USA. Center for Structural Oncology, Pennsylvania State University, University Park, PA16802, USA.
Deborah F. Kelly
Affiliation:
Department of Biomedical Engineering, Pennsylvania State University, University Park, PA, USA. Materials Research Institute, Pennsylvania State University, University Park, PA, USA. Center for Structural Oncology, Pennsylvania State University, University Park, PA16802, USA.

Abstract

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Type
Soft Matter and Biological Specimens
Information
Microscopy and Microanalysis , Volume 27 , Supplement S2: Proceedings of CISCEM 2021 - the 5th Conference on In-Situ and Correlative Electron Microscopy , November 2021 , pp. 19 - 20
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Copyright
Copyright © The Author(s), 2021. Published by Cambridge University Press on behalf of the Microscopy Society of America

References

References:

Demmert, A et al. , (2017) Visualizing Macromolecules in Liquid at the Nanoscale. In Liquid Cell Electron Microscopy, ed. Ross, F M, pp 356. Cambridge, New York: Cambridge University Press.Google Scholar
Varano, A et al. , Chemical Communications 51 (90) (2015), p. 16176.Google Scholar
Dukes, M et al. , Microscopy and Microanalysis 20 (2014), p. 338.Google Scholar
Jonaid, G et al. , Advanced Materials 2103221 (2021), In press 10.1002/adma.202103221CrossRefGoogle Scholar