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Ultrastructural Analysis of Cytoskeletal Networks in Neuronal Growth Cones by Light and Electron Microscopy

Published online by Cambridge University Press:  30 July 2021

Ryan Hylton
Affiliation:
1Penn State College of Medicine, Hershey, Pennsylvania, United States
Michael Grillo
Affiliation:
Penn State College of Medicine, United States
Jessica Heebner
Affiliation:
Penn State College of Medicine, United States
Matthew Swulius
Affiliation:
Penn State College of Medicine, United States

Abstract

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Type
Cryo-electron Tomography: Present Capabilities and Future Potential
Copyright
Copyright © The Author(s), 2021. Published by Cambridge University Press on behalf of the Microscopy Society of America

References

Vitriol, E, Zheng, J. Growth Cone Travel in Space and Time: The Cellular Ensemble of Cytoskeleton, Adhesion, and Membrane. Neuron (Cambridge, Mass.). 2012;73:1068-1081.CrossRefGoogle Scholar
Kerstein, PC, Nichol, RH, Gomez, TM. Mechanochemical regulation of growth cone motility. Frontiers in cellular neuroscience. 2015;9:244-244.Google ScholarPubMed
Lowery, LA, Vactor, DV. The trip of the tip: understanding the growth cone machinery. Nature reviews. Molecular cell biology. 2009;10:332-343.Google ScholarPubMed
Pollard, TD. Actin and actin-binding proteins. Cold Spring Harbor perspectives in biology. 2016;8:a018226.CrossRefGoogle ScholarPubMed
Flynn, KC, Bamburg, JR, Pak, CW. Actin-binding proteins take the reins in growth cones. Nature reviews. Neuroscience. 2008;9:136-147.Google Scholar
Dent, EW, Gupton, SL, Gertler, FB. The growth cone cytoskeleton in axon outgrowth and guidance. Cold Spring Harbor perspectives in biology. 2011;3:1-39.Google Scholar
De Arcangelis, A, Georges-Labouesse, E, Adams, JC. Expression of fascin-1, the gene encoding the actin-bundling protein fascin-1, during mouse embryogenesis. Gene Expression Patterns. 2004;4:637-643.CrossRefGoogle ScholarPubMed
Marsick, BM, Flynn, KC, Santiago-Medina, M, Bamburg, JR, Letourneau, PC. Activation of ADF/cofilin mediates attractive growth cone turning toward nerve growth factor and netrin-1. Developmental neurobiology (Hoboken, N.J.). 2010;70:565-588.CrossRefGoogle ScholarPubMed
Jayo, A, Parsons, M. Fascin: A key regulator of cytoskeletal dynamics. The international journal of biochemistry & cell biology. 2010;42:1614-1617.CrossRefGoogle ScholarPubMed
Cohan, CS, Welnhofer, EA, Zhao, L, Matsumura, F, Yamashiro, S. Role of the actin bundling protein fascin in growth cone morphogenesis: Localization in filopodia and lamellipodia. Cell motility and the cytoskeleton. 2001;48:109-120.3.0.CO;2-G>CrossRefGoogle ScholarPubMed
Kanellos, G, Frame, MC. Cellular functions of the ADF/cofilin family at a glance. Journal of cell science. 2016;129:3211-3218.Google ScholarPubMed
Gungabissoon, RA, Bamburg, JR. Regulation of Growth Cone Actin Dynamics by ADF/Cofilin. The journal of histochemistry and cytochemistry. 2003;51:411-420.CrossRefGoogle ScholarPubMed