Hostname: page-component-78c5997874-j824f Total loading time: 0 Render date: 2024-11-19T14:19:00.704Z Has data issue: false hasContentIssue false

Light-Activated Hydrophobic Adhesive for Shape-Memory Polymer NerveCuffs

Published online by Cambridge University Press:  28 December 2015

Victoria Wobser
Affiliation:
Department of Chemistry, University of Texas at Dallas, 800 W. Campbell Rd., Richardson, TX 75080, U.S.A.
Kejia Yang
Affiliation:
Department of Chemistry, University of Texas at Dallas, 800 W. Campbell Rd., Richardson, TX 75080, U.S.A.
Romil Modi
Affiliation:
Department of Bioengineering, University of Texas at Dallas
Wyatt Archer
Affiliation:
Department of Chemistry, University of Texas at Dallas, 800 W. Campbell Rd., Richardson, TX 75080, U.S.A.
Yogi Patel*
Affiliation:
Department of Biomedical Engineering, Georgia Institute of Technology, 313 Ferst Dr. NW, Atlanta, GA 30332, U.S.A.
Walter Voit
Affiliation:
Department of Chemistry, University of Texas at Dallas, 800 W. Campbell Rd., Richardson, TX 75080, U.S.A. Department of Bioengineering, University of Texas at Dallas Department of Materials Science and Engineering, University of Texas at Dallas
*
Get access

Abstract

In this study, three hydrophobic polymers are investigated as potential adhesivesfor a shape memory polymer nerve cuff. At room temperature, the adhesivecandidate exhibited a maximum lap shear stress of 1.7251 MPa, compared to0.87641 MPa and 2.1815 MPa for two commercially available biocompatibleadhesives.

Type
Articles
Copyright
Copyright © Materials Research Society 2015 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Hatsopoulos, N. G. and Donoghue, J. P., "The science of neural interface systems," Annual review of neuroscience, vol. 32, p. 249, 2009.Google Scholar
Harris, J., Capadona, J., Miller, R., Healy, B., Shanmuganathan, K., Rowan, S., et al. , "Mechanically adaptive intracortical implants improve the proximity of neuronal cell bodies," Journal of neural engineering, vol. 8, p. 066011, 2011.CrossRefGoogle Scholar
Ware, T., Simon, D., Rennaker, R. L., and Voit, W., "Smart polymers for neural interfaces," Polymer Reviews, vol. 53, pp. 108129, 2013.CrossRefGoogle Scholar
Ware, T., Simon, D., Arreaga-Salas, D. E., Reeder, J., Rennaker, R., Keefer, E. W., et al. , "Fabrication of responsive, softening neural interfaces," Advanced Functional Materials, vol. 22, pp. 34703479, 2012.CrossRefGoogle Scholar
Lang, N., Pereira, M. J., Lee, Y., Friehs, I., Vasilyev, N. V., Feins, E. N., et al. , "A blood-resistant surgical glue for minimally invasive repair of vessels and heart defects," Science translational medicine, vol. 6, pp. 218ra6-218ra6, 2014.Google Scholar
Li, Y., Cook, W. D., Moorhoff, C., Huang, W. C., and Chen, Q. Z., "Synthesis, characterization and properties of biocompatible poly (glycerol sebacate) pre-polymer and gel," Polymer International, vol. 62, pp. 534547, 2013.CrossRefGoogle Scholar
Simon, D., Ware, T., Marcotte, R., Lund, B. R., Smith, D. W. Jr, Di Prima, M., et al. , "A comparison of polymer substrates for photolithographic processing of flexible bioelectronics," Biomedical microdevices, vol. 15, pp. 925939, 2013.CrossRefGoogle Scholar
Ware, T., Simon, D., Hearon, K., Kang, T. H., Maitland, D. J., and Voit, W., "Thiol-Click Chemistries for Responsive Neural Interfaces," Macromolecular bioscience, vol. 13, pp. 16401647, 2013.CrossRefGoogle Scholar