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Enzymatic Synthesis of Chiral Lactones and Polyesters

Published online by Cambridge University Press:  21 February 2011

Arie L. Gutman
Arie L. Gutman*
Affiliation:
Department of Chemistry, Technion - Israel Institute of Technology, Haifa 32000, Israel
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Abstract

Lipases in organic solvents catalyse lactonisation or polymerisation of ω-hydroxyesters. Under these conditions the enzymes exhibit both enantioselectivity and prochiral selectivity. This approach was used to develop the synthesis of chiral γ-lactones and polyesters.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 174: Symposium R – Materials Synthesis Utilizing Biological Processes , 1989 , 217
Copyright
Copyright © Materials Research Society 1990

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