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Diamond Based Ion-Sensitive Field Effect Transistors for Cellular Biosensing

Published online by Cambridge University Press:  01 February 2011

Andrew Bennett ,
Olivier Gaudin ,
Oliver A. Williams ,
John S. Foord  and
Richard B. Jackman
Andrew Bennett
Affiliation:
University College London, University College London, London Centre for Nanotechnology, 17-19 Gordon Street, London, N/A, United Kingdom
Olivier Gaudin
Affiliation:
opmg@st-andrews.ac.uk, University of St Andrews, School of Physics and Astronomy, North Haugh, St Andrews, KY16 9SS, United Kingdom
Oliver A. Williams
Affiliation:
oliverwilliams@mac.com, University of Hasselt, IMO, Wetenschapspark 1, Diepenbeek, B-3590, Belgium
John S. Foord
Affiliation:
john.foord@chemistry.oxford.ac.uk, University of Oxford, Department of Chemistry, Mansfield Road, Oxford, OX1 3TA, United Kingdom
Richard B. Jackman
Affiliation:
r.jackman@ucl.ac.uk, University College London, London Centre for Nanotechnology, 17-19 Gordon Street, London, WC1H 0AH, United Kingdom
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Abstract

The use of a chemically inert and essentially biocompatible material for cellular biosensing is an attractive idea. In this context we have studied the operation of diamond-based ion-sensitive field effect transistors (ISFETs) within solutions of varying pH, and alkali-halide concentrations. In particular, we report the use of an inexpensive diamond substrate material, often referred to as ‘black’ diamond. pH sensitivity was observed when devices based on hydrogen-terminated p-type surfaces where employed, provide some surface oxidation was performed prior to their use. Variation in the threshold voltage for ISFET operation of the order of 20mV/pH unit was determined. In terms of operation in potassium iodide solution, we have shown that the device is shows selective sensitivity to the iodide species, despite the equi-molar presence of both K+ and I- species. The origin of this selectivity is discussed.

Keywords

diamonddevicessensor
Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 956: Symposium J – Diamond Electronics—Fundamentals to Applications , 2006 , 0956-J16-03
Copyright
Copyright © Materials Research Society 2007

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References

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