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Dual Functionalized Janus Nanocomposites for Targeted pH-Responsive Drug Delivery
Published online by Cambridge University Press: 17 February 2014
Abstract
A superparamagnetic Janus nanocomposite (SJNC) of polystyrene/Fe3O4@SiO2 was designed and developed with dual surface bearing functional groups for medical diagnosis and treatment. Folic acid (FA) and doxorubicin (DOX) were conjugated stepwise to the surfaces. SJNCs were found to enable simultaneous cell-targeted drug delivery via pH-responsive release mechanism.
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- MRS Online Proceedings Library (OPL) , Volume 1625: Symposium I – Multiscale Materials in the Study and Treatment of Cancer , 2014 , mrsf13-1625-i06-11
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- Copyright © Materials Research Society 2014