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Viscoelasticity and its Microscopic Characterization in Semiflexible Biopolymer Solutions

Published online by Cambridge University Press:  15 February 2011

F. C. Mackintosh ,
F. Gittes ,
B. Schnurr ,
P. D. Olmsted  and
C. F. Schmidt
F. C. Mackintosh
Affiliation:
Department of Physics & Biophysics Research Division, University of Michigan, Ann Arbor, MI 48109
F. Gittes
Affiliation:
Department of Physics & Biophysics Research Division, University of Michigan, Ann Arbor, MI 48109
B. Schnurr
Affiliation:
Department of Physics & Biophysics Research Division, University of Michigan, Ann Arbor, MI 48109
P. D. Olmsted
Affiliation:
Department of Physics, University of Leeds, Leeds, LS2 9JT, United Kingdom
C. F. Schmidt
Affiliation:
Department of Physics & Biophysics Research Division, University of Michigan, Ann Arbor, MI 48109
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Abstract

Plant and animal cells contain a complex polymeric network known as the cytoskeleton. A principal component of this is the actin cortex, a gel-like network of F-actin protein filaments. Recently, solutions of reconstituted F-actin have provided in vitro models of the actin cortex, as well as excellent model systems in which to study semiflexible polymers. We describe models of viscoelasticity in semifexible polymers, and report theoretical and experimental results for thermal fluctuations of embedded particles, which act as local viscoelastic probes of soft materials such as biopolymer solutions. Specifically, we report high-frequency scaling behavior of the shear modulus, as the 3/4 power of frequency, in contrast with the behavior of flexible polymer systems.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 489: Symposium K – Materials Science of the Cell , 1997 , 39
Copyright
Copyright © Materials Research Society 1998

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