Different portrayals of visions from the Apocalypse exhibit particular ‘readings’ of the text and reflect some of the contrasting exegetical approaches familiar to biblical exegetes. The article surveys the various ways in which artists have sought to enter into, and re-express, the content and character of the visions of John, offers synchronic interpretations of the Apocalypse, gives varying interpretations of the four horsemen, explores the dialectic between heaven and earth in ecclesial and eschatological readings, and engages in political interpretations of the Apocalypse. Historical analogies are offered in order to compare the exercise of imagination in art with other examples of visualizing biblical texts.