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The age and sex of the host as factors affecting the host–parasite relationship of the third-stage larva of Amplicaecum robertsi Sprent & Mines, 1960, in the laboratory mouse

Published online by Cambridge University Press:  06 April 2009

Colin Dobson
Colin Dobson
Affiliation:
Department of Parasitology, University of Queensland, St Lucia, Brisbane, Queensland, Australia
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Extract

There was no difference between the worm burdens or the lengths of the worms recovered from sexually immature male and female mice infected with Amplicaecum robertsi.

In mice older than 70 days there were fewer larvae recovered from the female than the male host. The larvae were also longer in the male than in the female mouse.

The suckling mouse harboured fewer larvae than the weanling; the susceptibility of the mouse continued to increase with increasing age until the one-hundredth day in the males and the seventy-fifth day in the females. In animals older than this an age resistance was apparent. It is suggested that the much lower susceptibility of the suckling mouse is due to the small gut and villi size reducing the establishment of the larvae.

Worm growth also varied with host age, the longest larvae being recovered from the suckling mice and successively smaller worms from each older age group up to the seventy-fifth day, beyond which there was no significant change in worm growth with age of the host. There was no difference between the worm burdens and the lengths of the worms recovered from 90-day-old mice. The injection of testosterone had little or no effect on the host–parasite relationship of gonad-ectomized animals. Larvae from gonadectomized mice were significantly shorter than those from the intact hosts.

Type
Research Article
Information
Parasitology , Volume 56 , Issue 3 , August 1966 , pp. 399 - 406
Copyright
Copyright © Cambridge University Press 1966

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References

REFERENCES

Dobson, C. (1960). An investigation of the host–parasite relations and host specificity of Nematospiroides dubius Baylis, 1962; Heligmosomidae, a mouse nematode in its normal and an abnormal host. Thesis, University Library, Sheffield.Google Scholar
Dobson, C. (1961 a). Certain aspects of the host–parasite relationship of Nematospiroides dubius (Baylis). I. Resistance of male and female mice to experimental infections. Parasitology 51, 173–9.CrossRefGoogle ScholarPubMed
Dobson, C. (1961 b). Certain aspects of the host–parasite relationship of Nematospiroides dubius (Baylis). II. The effect of sex on experimental infections in the rat (an abnormal host). Parasitology 51, 499–510.CrossRefGoogle ScholarPubMed
Dobson, C. (1961 c). Certain aspects of the host–parasite relationship of Nematospiroides dubius (Baylis). III. The effect of a milk diet on experimental infections in the adult male mouse. Parasitology 51, 511–4.CrossRefGoogle ScholarPubMed
Dodson, C. (1962 a). Certain aspects of the host–parasite relationship of Nematospiroides dubius (Baylis). IV. The effect of the host's age on experimental infections in the mouse and rat. Parasitology 52, 31–40.Google Scholar
Dobson, C. (1962 b). Certain aspects of the host–parasite relationship of Nematospiroides dubius (Baylis). V. Host specificity. Parasitology 52, 41–8.CrossRefGoogle Scholar
Dobson, C. (1965 a). The relationship between worm population density, host survival and the growth of the third-stage larva of Amplicaecum robertsi Sprent and Mines, 1960, in the mouse. Parasitology 55, 183–93.CrossRefGoogle ScholarPubMed
Dobson, , (1965 b). The effects of host sex and age on the host–parasite relationship of the third-stage larva of Amplicaecum robertsi Sprent and Mines, 1960, in the laboratory rat. Parasitology 55, 303–11.CrossRefGoogle ScholarPubMed
Kao, K. Y. T. & McGavack, T. H. (1959). Connective tissue. I. Age and sex influence on protein composition of rat tissue. Proc. Soc. exp. Biol. Med. 101, 153–7.CrossRefGoogle Scholar
Lewert, R. M. & Mandlowitz, S. (1963). Innate immunity to Schistosoma mansoni relative to the state of the connective tissue. Ann. N. Y., Acad. Sci. 113, 54–62.CrossRefGoogle Scholar
Sprent, J. F. A. (1963). The life history and development of Amplicaecum robertsi, an ascaridoid nematode of the python (Morelia spilotes variegatus). I. Morphological and functional significance of larval stages. Parasitology 53, 7–38.CrossRefGoogle Scholar