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Characterization of cell types in the parenchyma of Schistosoma mansoni

Published online by Cambridge University Press:  06 April 2009

Magdalena Reissig
Magdalena Reissig
Affiliation:
Department of Pathobiology, School of Hygiene and Public Health, The Johns Hopkins University, Baltimore, Maryland, 21205
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Summary

A study has been made of the parenchyma of adult male Schistosoma mansoni by electron microscopy. Four different cell types have been characterized: one corresponding to cell bodies of the integument, two to muscle cells and another one to nerve cells with a possible neurosecretory function. The cytoplasm of the integument cell bodies is characterized by rod-shaped and round membrane-bound cytoplasmic bodies with a dense core, measuring 1200 to 2000 Å, similar to those found in the integument. One type of muscle cell has a large, clear nucleus, characteristic cytoplasmic vacuoles measuring up to 1 μm with a finely granular content and numerous free ribosomes. The other type of muscle cell is much smaller, with clumped nuclear chromatin and scanty perinuclear cytoplasm. Both types of cells give rise to muscle fibres which are morphologically distinct from the perinuclear cytoplasm. The nerve cells contain electron-dense, membrane-bound vesicles-ranging in size from 1000 to 3000 Å, similar to those found in nerve axons.

Appreciable extracellular matrix has only been found under the integument and surrounding the processes of the integument cell bodies. This observation and the fact that silver methenamine after periodic oxidation stains intensely both the extracellular substance and the rod-shaped and round cytoplasmic bodies of the integument cells, suggests that these integument cells may be involve the production of extracellular matrix.

This investigation was supported by grant AI 07806 from the U.S.P.H.S.

The technical assistance of Mrs Lucille Jeffries and the photographic assistance of Mr William Douglas are acknowledged. This investigation was supported by the United States–Japan Cooperative Medical Science Program administered by the National Institute of Allergy and Infectious Diseases of the National Institutes of Health, Department of Health, Education and Welfare.

Type
Research Article
Information
Parasitology , Volume 60 , Issue 2 , April 1970 , pp. 273 - 279
Copyright
Copyright © Cambridge University Press 1970

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