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Immunity to Trichinella spiralis II. Immunity produced by the adult worm in mice

Published online by Cambridge University Press:  06 April 2009

D. A. Denham
D. A. Denham
Affiliation:
Department of Animal Pathology, Madingley Road, Cambridge*
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Extract

It has been shown that the 5th or adult stage of Trichinella spiralis stimulates strong immunity in mice. This was shown using a transfer technique and irradiated worms. A comparison between the immunity produced by a normal infection and one which has been irradiated is made and explanations offered to explain the fact that less immunity is stimulated by irradiated larvae.

I would like to express my gratitude to H.M. Treasury and to the Agricultural Research Council for financial support during the time that this work was conducted. I would also like to thank Professor W.I.B. Beveridge, within whose department this work was conducted, for the facilities provided. I would also like to record my gratitude to Dr W. C. Campbell for the many stimulating discussions we have had on the subject of Trichinella.

Type
Research Article
Information
Parasitology , Volume 56 , Issue 4 , November 1966 , pp. 745 - 751
Copyright
Copyright © Cambridge University Press 1966

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References

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