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The inhibition by p-aminobenzoic acid of the development of paludrine-resistance as produced by sulphonamides in plasmodium gallinaceum

Published online by Cambridge University Press:  06 April 2009

Ann Bishop  and
Elspeth W. McConnachie
Ann Bishop
Affiliation:
Molteno Institute, University of Cambridge
Elspeth W. McConnachie
Affiliation:
Molteno Institute, University of Cambridge
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Extract

A strain of Plasmodium gallinaceum has been treated for 10 weeks with sulphadiazine (5 mg./20 g.) in the presence of p-aminobenzoic acid in doses (0·5 mg./ 20 g.) inhibiting the sulphadiazine. No resistance to paludrine or to sulphadiazine has developed.

Type
Research Article
Information
Parasitology , Volume 41 , Issue 1-2 , July 1951 , pp. 105 - 109
Copyright
Copyright © Cambridge University Press 1951

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References

REFERENCES

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