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Interactions between the intestinal flagellates Giardia muris and Spironucleus muris and the blood parasites Babesia microti, Plasmodium yoelii and Plasmodium berghei in mice

Published online by Cambridge University Press:  06 April 2009

Sara J. Brett  and
F. E. G. Cox
Sara J. Brett
Affiliation:
Department of Zoology, King's College London, Strand, London WC2R 2LS
F. E. G. Cox
Affiliation:
Department of Zoology, King's College London, Strand, London WC2R 2LS
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Summary

In mice infected with the intestinal flagellates Giardia muris or Spironucleus muris, together with the blood parasites Babesia microti or Plasmodium yoelii, there is a temporary decrease of flagellate cyst output coincident with the peak of the blood parasite infections, followed by a rapid return to normal levels. This decrease in cyst output is correlated with decreased numbers of trophozoites in the small intestine. The effect on S. muris is more marked than that on G. muris. Neither blood parasites has any effect on the total duration of the flagellate infection and the flagellates do not affect the blood parasites. In mice infected with G. muris or S. muris and P. berghei there is also a decrease in cyst output but this is less apparent than in infections with B. microti or P. yoelii because of the fatal nature of the P. berghei infection. It is suggested that the decrease in cyst output is probably due to changes in the contents of the small intestine or to non-specific immunological factors rather than to specific immunological changes.

Type
Research Article
Information
Parasitology , Volume 85 , Issue 1 , August 1982 , pp. 101 - 110
Copyright
Copyright © Cambridge University Press 1982

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