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Malarial S-antigens from man and owl monkey infected with Plasmodium falciparum

Published online by Cambridge University Press:  06 April 2009

R. J. M. Wilson  and
A. Voller
R. J. M. Wilson
Affiliation:
M.R.C. Laboratories, Fajara, The Gambia, West Africa
A. Voller
Affiliation:
Nuffield Institute of Comparative Medicine, Zoological Society of London, Regent's Park, London, N. W. 1
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Extract

Owl monkeys infected with the Malayan Camp strain of Plasmodium falciparum were found to have malarial antigens in their serum at the height of infection. The antigens were identical with certain malarial S-antigens present in the sera of West African (Gambian) children acutely infected with P. falciparum. The infected owl monkey thus appears to provide an experimental model which is relevant to the study of the serology of human malaria.

Type
Research Article
Information
Parasitology , Volume 61 , Issue 3 , December 1970 , pp. 461 - 464
Copyright
Copyright © Cambridge University Press 1970

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References

REFERENCES

Brown, I. N., Brown, K. N. & Hills, L. A. (1968). Immunity to malaria. The antibody response to antigenic variation to Plasmodium knowlesi. Immunology 14, 127–38.Google ScholarPubMed
Gieman, Q. M. & Meagher, M. J. (1967). Susceptibility of a New World monkey to Plasmodium falciparum from man. Nature, London 215, 437–9.CrossRefGoogle Scholar
McGregor, I. A., Turner, M. W., Williams, K. & Hall, P. (1968). Soluble antigens in the blood of African patients with severe Plasmodium falciparum malaria. The Lancet, 1, 881–4.CrossRefGoogle ScholarPubMed
Ouchterlony, O. (1958). Diffusion-in-gel methods for immunological analysis. Progress in Allergy 5, 1–78.Google ScholarPubMed
Turner, M. W. & McGregor, I. A. (1969). Studies on the immunology of human malaria. I. Preliminary characterisation of antigens in Plasmodium falciparum infections. Clinical and Experimental Immunology 5, 1–16.Google ScholarPubMed
Voller, A., Richards, W. H. G., Hawkey, C. M. & Ridley, D. S. (1969). Human malaria (Plasmodium falciparum) in owl monkeys (Aotus trivirgatus). Journal of Tropical Medicine and Hygiene 72, 153–60.Google ScholarPubMed
Voller, A. & Richards, W. H. G. (1970). Immunity to Plasmodium falciparum in owl monkeys. Zeitschrift fur Tropenmedizin und Parasitologie. 21, 159–166.Google ScholarPubMed
Wilson, R. J. M. (1970). Antigens and antibodies associated with Plasmodium falciparum infections in West Africa. Transactions of the Royal Society for Tropical Medicine and Hygiene 64, 547–55.CrossRefGoogle ScholarPubMed
Wilson, R. J. M., McGregor, I. A., Hall, P. J., Williams, K. & Bartholomew, R. (1969). Antigens associated with Plasmodium falciparum infections in man. Lancet 2, 201–5.CrossRefGoogle ScholarPubMed