Hostname: page-component-84b7d79bbc-4hvwz Total loading time: 0 Render date: 2024-07-25T07:23:27.750Z Has data issue: false hasContentIssue false
  • English
  • Français

Morphological and taxonomic studies on mammalian trypanosomes

VI. Further observations on the absence of the kinetoplast in Trypanosoma evansi

Published online by Cambridge University Press:  06 April 2009

Cecil A. Hoare  and
S. C. J. Bennett
Cecil A. Hoare
Affiliation:
Wellcome Bureau of Scientific Research, London
S. C. J. Bennett
Affiliation:
Veterinary Research Laboratory, Khartoum
Get access Rights & Permissions [Opens in a new window]

Extract

An account is given of two aberrant strains of Trypanosoma evansi recovered from Sudanese camels.

One of these—like the four other ones described in a previous paper—was totally akinetoplastic (= akinetonucleate) and has been kept under observation for eighteen months in the course of which the aberrant condition remained unchanged.

The second strain was characterized by a wide fluctuation in the proportion of akinetoplastic forms which ranged from zero to over 70% at different periods of observation.

The bearing of this fluctuation upon the production of akinetoplastic strains is discussed and it is concluded that these probably arise in nature either indirectly, through the inoculation by the insect vector of new hosts with trypanosomes lacking the kinetoplast, or directly, by the strain becoming totally akinetoplastic within the same host.

From an analysis of the fluctuating strain it would appear that the variation in the proportion of akinetoplastic trypanosomes depends upon the following factors: (1) irregular division (without bipartition of the kinetoplast), which is the most important factor; (2) rate of reproduction of normal and aberrant individuals; (3) mortality rate of the different types of dividing and non-dividing forms.

The primary cause of the disappearance of the kinetoplast could not be ascertained.

Type
Research Article
Information
Parasitology , Volume 30 , Issue 4 , December 1938 , pp. 529 - 542
Copyright
Copyright © Cambridge University Press 1938

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Alexeieff, A. (1917). Sur la fonction glycoplastique du kinétoplaste (=kinétonucleus) chez les flagellés. C.R. Soc. Biol., Paris, 80, 512.Google Scholar
Fry, W. B. (1911). Animal trypanosomiases in the Anglo-Egyptian Sudan. 4th Rep. Wellcome Trop. Res. Lab. Khartoum, (A), p. 41.Google Scholar
Hoare, C. A. (1938). Morphological and taxonomic studies on mammalian trypanosomes. V. The diagnostic value of the kinetoplast. Trans. Roy. Soc. trop. Med. Hyg. 32, 333.CrossRefGoogle Scholar
Hoare, C. A. & Bennett, S. C. J. (1937). Morphological and taxonomic studies on mammalian trypanosomes. III. Spontaneous occurrence of strains of Trypanosoma evansi devoid of the kinetonucleus. Parasitology, 29, 43.CrossRefGoogle Scholar
Lwoff, A. (1932). Recherches biochimiques sur la nutrition des protozoaires: Le pouvoir de synthèse. Monogr. Inst. Pasteur, Paris.Google Scholar
Lwoff, A. & Lwoff, M. (1931). Recherches morphologiques sur Leptomonas ctenocephali Fanth. (Trypanosomide). Remarques sur l'appareil parabasal. Bull. Biol. 65, 170.Google Scholar
Wenyon, C. M. (1928). The loss of the parabasal body in trypanosomes. Trans. Roy. Soc. trop. Med. Hyg. 22, 85.CrossRefGoogle Scholar