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Studies on the immunity of albino mice to Trichuris muris

The stimulation of immunity by chemically abbreviated infections

Published online by Cambridge University Press:  06 April 2009

D. Wakelin
D. Wakelin
Affiliation:
Department of Zoology, Bedford College, London, N. W. 1
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Extract

The immunogenicity of larval Trichuris muris in Schofield strain albino mice has been studied using infections abbreviated by chemotherapy. When mice were exposed to an initial infection lasting from 7 to 14 days their immunity to reinfection increased progressively, but the immunity stimulated by abbreviated infections was less than that stimulated by uninterrupted immunizing infections which last for approximately 16–18 days. The immune response of mice to T. muris appears to be stimulated by, and effective against, larvae of all ages and does not show stage specificity.

Type
Research Article
Information
Parasitology , Volume 59 , Issue 3 , August 1969 , pp. 549 - 555
Copyright
Copyright © Cambridge University Press 1969

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References

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