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The Fixation of Rabies Virus in the Monkey (Macacus rhesus) with a Study of the Appearance of Negri Bodies in the Different Passages
Published online by Cambridge University Press: 06 April 2009
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Pasteur, in May 1884, showed that if the rabies virus of the dog was passed from rabbit to rabbit, or guinea-pig to guinea-pig, it gradually became exalted in virulence and fixed in incubation period for these rodents. This fixed virus remained exalted in virulence when inoculated subdurally into other animals. Magendie held the opinion that the rabies virus, when transmitted by bites from dog to dog, lost its virulence by about the fifth passage.
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- Copyright © Cambridge University Press 1913