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The glucose metabolism of adult Ostertagia circumcincta, in vitro

Published online by Cambridge University Press:  06 April 2009

P. F. V. Ward ,
W. J. Coadwell  and
N. S. Huskisson
P. F. V. Ward
Affiliation:
Biochemistry Department, A. R. C. Institute of Animal Physiology, Babraham, Cambridge CB2 4AT
W. J. Coadwell
Affiliation:
Biochemistry Department, A. R. C. Institute of Animal Physiology, Babraham, Cambridge CB2 4AT
N. S. Huskisson
Affiliation:
Biochemistry Department, A. R. C. Institute of Animal Physiology, Babraham, Cambridge CB2 4AT
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Summary

Adult Ostertagia circumcincta from freshly killed sheep were incubated at 39 °C in a medium containing inorganic salts, antibiotics and D-[U-14C] glucose. The worms appeared healthy even after incubation for as long as 72 h. All the radioactivity was recovered either within the worms or in the incubation vessel in the form of metabolic products or unmetabolized glucose. Incubations were carried out at low oxygen tension except for those in which CO2 was measured. These were either aerobic or anaerobic. In terms of both quantity and radioactivity the main metabolic products of glucose were CO2, propan-1-ol, acetate and propionate. Smaller amounts of ethanol, lactate and succinate were formed. The results are compared with those found for the similar nematode Haemonchus contortus.

Type
Research Article
Information
Parasitology , Volume 82 , Issue 1 , February 1981 , pp. 17 - 22
Copyright
Copyright © Cambridge University Press 1981

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References

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