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Invasion of chicken caecal and intestinal lamina propria by crypt epithelial cells infected with coccidia

Published online by Cambridge University Press:  06 April 2009

M. A. Fernando ,
A. M. Lawn ,
M. Elaine Rose  and
M. A. Al-Attar
M. A. Fernando
Affiliation:
Department of Pathology, Ontario Veterinary College, University of Guelph, Guelph, Ontario, CanadaNIG 2 W1
A. M. Lawn
Affiliation:
Department of Houghton Poultry Research Station, Houghton, Huntingdon, Cambs. PE17 2DA
M. Elaine Rose
Affiliation:
Department of Houghton Poultry Research Station, Houghton, Huntingdon, Cambs. PE17 2DA
M. A. Al-Attar
Affiliation:
Department of Pathology, Ontario Veterinary College, University of Guelph, Guelph, Ontario, CanadaNIG 2 W1
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Summary

The development of second generation schizonts of Eimeria necatrix and E. tenella was studied with the electron microscope. Invasion of the crypt epithelial cells by merozoites of the first generation schizonts caused changes in the morphology of the infected cells and stimulated their migration into the lamina propria through breaks which appeared in the basement membrane of the crypts. Second generation schizonts developed in the lamina propria within these crypt cells whose epithelial origin was confirmed by their interconnection by desmosomes and tight junctions and by their possession of characteristic microvilli. A comparison is made between this invasion of the lamina propria by parasitized cells and invasion of connective tissue by malignant epithelial cells; the possible mechanisms involved are discussed.

Type
Research Article
Information
Parasitology , Volume 86 , Issue 3 , June 1983 , pp. 391 - 398
Copyright
Copyright © Cambridge University Press 1983

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