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Structural changes in the bovine nematode Haemonchus placei, that may be associated with host immune response

Published online by Cambridge University Press:  06 April 2009

E. Harness ,
K. Smith  and
Patricia Bland
E. Harness
Affiliation:
Institute for Research on Animal Diseases, Compton, Nr Newbury, Berks.
K. Smith
Affiliation:
Institute for Research on Animal Diseases, Compton, Nr Newbury, Berks.
Patricia Bland
Affiliation:
Institute for Research on Animal Diseases, Compton, Nr Newbury, Berks.
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Extract

The structure of H. placei adult worms, obtained from calves at 4, 7, 10 or 11–13 weeks after primary infection, has been studied. A reorganization of rough endoplasmic reticuhim in the cytoplasm of the gut cells was seen at 10 weeks and this was followed by marked vacuolation of many of these cells, associated with an increase in lipid production. Increases of lipid were also found in the hypodermis, lateral cords and occasionally muscle cells of worms examined at 11–13 weeks after infection.

It is suggested that these changes are the result of the host immune response, because they resemble changes which occur in the rat nematode Nippostrongylus brasiliensis and which are known to be caused by host immunity.

Type
Research Article
Information
Parasitology , Volume 66 , Issue 1 , February 1973 , pp. 199 - 205
Copyright
Copyright © Cambridge University Press 1973

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References

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