In his paper, “Explanations of Irrelevance” (1983), Paul Horwich proposes an amended version of hypothetico-deductivism, (H-D*). In this discussion note it is shown that (H-D*) has the consequence that “A is a non-black raven” confirms “All ravens are black” relative to any tautology! It is noted that Horwich's (H-D*) bears a strong resemblance to Hempel's prediction criterion of confirmation and that the prediction criterion faces the same obstacle. A related problem for hypothetico-deductivism in its simplest form—that is, E confirms H iff E is an (observational) consequence of H—is displayed. The discussion concludes with a suggestion about how (H-D*) and simple hypothetico-deductivism might be amended in order to avoid these results.