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Microcirculatory Support by Fluorocarbons

Published online by Cambridge University Press:  28 June 2012

N.S. Faithfull ,
W. Erdmann ,
M. Fennema ,
A. Smith ,
W. van Alphen  and
A. Kok
N.S. Faithfull
Affiliation:
Department of Anesthesia, Erasmus University, Rotterdam, The Netherlands.
W. Erdmann
Affiliation:
Department of Anesthesia, Erasmus University, Rotterdam, The Netherlands.
M. Fennema
Affiliation:
Department of Anesthesia, Erasmus University, Rotterdam, The Netherlands.
A. Smith
Affiliation:
Department of Plastic Surgery, Erasmus University, Rotterdam, The Netherlands.
W. van Alphen
Affiliation:
Department of Plastic Surgery, Erasmus University, Rotterdam, The Netherlands.
A. Kok
Affiliation:
Department of Anesthesia, Erasmus University, Rotterdam, The Netherlands.
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Extract

Fluorocarbons, or more strictly perfluorochemical (PFC) containing plasma substitutes have a high solubility for the respiratory gases, a desirable feature for a plasma substitute. This was dramatically demonstrated by their ability to sustain life for many hours in rats almost completely devoid of red cells. The ability of PFCs to carry oxygen exceeds that of other hemodilutents and they have been shown to produce better oxygenation under conditions of hemodilution than hydroxyethyl starch, dextran solutions or stroma-free hemoglobin solutions.

Type
Clinical Topics
Information
Prehospital and Disaster Medicine , Volume 3 , Issue 2: Contributions from the Fouth World Congress on Emergency and Disaster Medicine, Brighton, England May, 1985 , 1987 , pp. 53 - 58
Copyright
Copyright © World Association for Disaster and Emergency Medicine 1987

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