Hair follicles have been described as dynamic structures in which cell proliferation, migration and synthesis of macromolecules occur. Detailed knowledge is still lacking in areas related to cell proliferation, growth and migration and it has been suggested that our limited understanding of mechanisms regulating hair growth has been partly caused by the lack of reliable in vitro models. In the work desribed here, we have adapted a recent technique developed for the isolation and maintenance of human hair follicles in vitro (Philpott et al. 1990), to the isolation of intact anagen follicles from the Angora goat and report on their growth over 4 days and aspects of metabolic activity over 5 days in culture.