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Leptin is a signal of adiposity in fetuses of pregnant ewes fed at or above maintenance energy requirements

Published online by Cambridge University Press:  20 November 2017

BS Mühlhäusler ,
CT Roberts ,
JR McFarlane ,
KG Kauter  and
IC McMillen
BS Mühlhäusler
Affiliation:
Department of Physiology, Adelaide University, SA 5005, Australia
CT Roberts
Affiliation:
Department of Obstetrics and Gynaecology, Adelaide University, SA 5005, Australia
JR McFarlane
Affiliation:
Department Animal Science, University of New England, Armidale NSW, Australia
KG Kauter
Affiliation:
Department Animal Science, University of New England, Armidale NSW, Australia
IC McMillen
Affiliation:
Department of Physiology, Adelaide University, SA 5005, Australia
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Extract

In the adult, circulating leptin concentrations are dependent on body fat content and on current nutrient intake. Whilst leptin concentrations in umbilical cord blood correlate with fetal adiposity in the human neonate, it is unknown whether leptin acts as a signal of fat mass before birth or whether changes in maternal nutrient intake alter plasma leptin concentrations in the fetus. We have therefore investigated the relationship between fetal plasma leptin concentrations and fetal fat mass in pregnant ewes fed at or above maintenance energy requirements.

Type
Theatre Presentations
Information
Proceedings of the British Society of Animal Science , Volume 2002 , 2002 , pp. 5
Copyright
Copyright © The British Society of Animal Science 2002

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