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IV.—The Storage of Red Cells

Published online by Cambridge University Press:  05 December 2011

J. Blagdon
J. Blagdon
Affiliation:
North-East Metropolitan Regional Blood Transfusion Centre, Crescent Drive, Brentwood, Essex.
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Extract

In 1967 when Tullis opened a discussion on ‘Methods and standards of blood transfusion’ he said that the discovery of citrate, which made it possible to store blood for a few days before transfusion, was perhaps the worst step that ever took place, because it made it possible for clinicians to abuse blood. Now they could collect it in a bottle, put it in a refrigerator for a few days and fully inactivate many labile components such as platelets, anti-haemophilic globulin, leucocytes and lipoproteins [1].

When blood is stored prior to transfusion there is a deterioration in the viability of the red cell in addition to other components. This has been assessed mainly on the post-transfusion survival, but in recent years more interest has been shown in the oxygen-carrying capacity.

Type
Research Article
Information
Proceedings of the Royal Society of Edinburgh, Section B: Biological Sciences , Volume 71 , supplement S1 , 1972 , pp. s35 - s46
Copyright
Copyright © Royal Society of Edinburgh 1972

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References

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