Hostname: page-component-84b7d79bbc-fnpn6 Total loading time: 0 Render date: 2024-07-31T10:12:57.342Z Has data issue: false hasContentIssue false

III.—Genetics of Gametes. III. Strain Differences in Spermatozoa from Eight Inbred Strains of Mice*

Published online by Cambridge University Press:  11 June 2012

R. A. Beatty
Affiliation:
Institute of Animal Genetics, Edinburgh. Agricultural Research Council Unit of Animal Genetics.
K. N. Sharma*
Affiliation:
Institute of Animal Genetics, Edinburgh.
*
Present address: Department of Zoology, Cotton College, Gauhati, Assam, India.
Get access

Synopsis

In animals, the expression of genetic factors has been studied mainly after fertilization, in the embryo or the adult. The study of genetic effects on the gametes themselves has been called the genetics of gametes. As evidence of such genetic effects on gametes, numerous differences have been found in the characteristics of spermatozoa from eight inbred strains of mice. The spermatozoan characteristics studied are mainly dimensional, but also relate to the physiological maturation of spermatozoa and possibly to semen fertility. The dimensional characteristics of spermatozoa are insulated, to an unusual degree, from the effects of environmental and other factors. The genetics of gametes can be regarded as the study of the genetics of the carriers of genes from one generation to the next; this has relevance to general genetics, and also to experiments for controlling the transmission of hereditary factors from parent to offspring.

Type
Research Article
Copyright
Copyright © Royal Society of Edinburgh 1961

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Footnotes

*

This paper was assisted in publication by a grant from the Carnegie Trust for the Universities of Scotland.

References

References to Literature

Anderson, R. L., and Bancroft, T. A., 1952. Statistical Theory in Research. McGraw-Hill: New York, Toronto, London.Google Scholar
Beatty, R. A., 1954. “Haploid Rodent Eggs”, Proc. IX Int. Congr. Genet., Bellagio, 1954; Caryologia 6, Suppl. Part II, 784.Google Scholar
Beatty, R. A., 1956. “Melanizing Activity of Semen from Rabbit Males of Different Genotype”, Proc. Roy. Phys. Soc, 25, 3944.Google Scholar
Beatty, R. A., 1957 a. “Genetics of Mammalian Gametes”, Res. Rep., 19551957, Institute of Animal Genetics, Edinburgh. Edited by Waddington, C. H., 4648.Google Scholar
Beatty, R. A., 1957 b. “Nigrosin-eosin Staining of Rabbit Spermatozoa and the Fertility of Semen”, Proc. Roy. Soc. Edin., B, 67, 131.Google Scholar
Beatty, R. A., 1957 c. Parthenogenesis and Polyploidy in Mammalian Development. Cambridge Monographs in Experimental Biology. Cambridge University Press.Google Scholar
Beatty, R. A., 1958 a. In “Cytodifferentiation and Genic Endowment”, Cytodifferentiation, edited by Rudnick, D.. Report from the Developmental Biology Conference Series 1956. Chapter I, 10–11. Chicago University Press.Google Scholar
Beatty, R. A., 1958 a. “Genetics of Mammalian Spermatozoa”, Proc. X Int. Congr. Genet., Montreal, 1958, p. 16.Google Scholar
Beatty, R. A., 1960. “Chromosomal Determination of Sex in Mammals”, Mem. Soc. Endocrin. Edited by Austin, C. R., 7, 45–48.CrossRefGoogle Scholar
Beatty, R. A., and Fischberg, M., 1949. “Spontaneous and Induced Triploidy in Pre-implantation Mouse Eggs”, Nature, Lond., 163, 807808.CrossRefGoogle ScholarPubMed
Beatty, R. A., 1951. “Heteroploidy in Mammals. I. Spontaneous Heteroploidy in Pre-Implantation Mouse Eggs”, J. Genet., 50, 345359.Google Scholar
Beatty, R. A., and Napier, R. A. N., 1960 a.Genetics of Gametes. I. A Quantitative Analysis of Five Characteristics of Rabbit Spermatozoa”, Proc. Roy. Soc. Edin., B, 68, 116.Google Scholar
Beatty, R. A., and Napier, R. A. N., 1960 b.Genetics of Gametes. II. Strain Differences in Characteristics of Rabbit Spermatozoa”, Proc. Roy. Soc. Edin., B, 68, 1724.Google Scholar
Bishop, M. W. H., 1955Inter-relationships of Semen Characteristics”, Proc. Soc. Stud. Pert., 7, 4865.Google ScholarPubMed
Braden, A. W. H., 1956. Studies on mammalian ova. Ph.D. Thesis, Edinburgh University.Google Scholar
Braden, A. W. H., 1957 a.Differences between Inbred Strains of Mice in the Morphology of the Gametes”, Anat. Rec. 127, 270271 (Abstr.).Google Scholar
Braden, A. W. H., 1957 b. “Variation Between Strains In The Incidence Of Various Abnormalities Of Egg Maturation And Fertilization In The Mouse”, J. Genet., 55, 476496.Google Scholar
Braden, A. W. H., 1958 a. “Influence of Time of Mating on the Segregation Ratio of Alleles at the T Locus in the House Mouse”, Nature, Lond., 181, 786787.CrossRefGoogle Scholar
Braden, A. W. H., 1958 b. “Strain Differences in the Incidence of Polyspermia in Rats after Delayed Mating”, Fertil. and Steril., 9, 243246.CrossRefGoogle ScholarPubMed
Carter, T. C, Dunn, L. C, Falconer, D. S., Grüneberg, H., Heston, W. E. and Snell, G. D., 1952. “Standardized Nomenclature for Inbred Strains of Mice”, Cancer Res., 12, 602613.Google Scholar
Clayton, R. M., and Edwards, R. G., 1957. Res. Rep., 1955-1957, Institute of Animal Genetics, Edinburgh. Edited by Waddington, C. H., p. 47.Google Scholar
Duncan, D. B., 1955. “Multiple Range and Multiple F Tests”, Biometrics, 11, 142.CrossRefGoogle Scholar
Edwards, R. G., 1955. “Selective Fertilization following the use of Sperm Mixtures in the Mouse”, Nature, Lond., 175, 215.CrossRefGoogle ScholarPubMed
Gordon, M. J., 1958. “Control of Sex Ratio in Rabbits by Electrophoresis of Spermatozoa”, Proc. Nat. Acad. Sci. Wash., 43, 913918.CrossRefGoogle Scholar
Hancock, J. L., 1951. “A Staining Technique for the Study of Temperature-shock in Semen”, Nature, Lond., 167, 323.CrossRefGoogle Scholar
Hancock, J. L., 1953. “The Spermatozoa Of Sterile Bulls”, J. Exp. Biol., 30, 5056.CrossRefGoogle Scholar
Heston, W. E., 1949. “Development of Inbred Strains in the Mouse and their use in Cancer Research”, Roscoe B. Jackson Mem. Lab., 20th Commemoration Lectures on Genetics, Cancer, Growth and Social Behaviour. Bar Harbor Times, Bar Harbor, Maine.Google Scholar
Landsteiner, K., and Levine, P., 1926. “On Group Specific Substances in Human Spermatozoa”, J. Immunol., 12, 415418.CrossRefGoogle Scholar
Lindahl, P. E., 1956. “Counter-streaming Centrifugation of Bull Spermatozoa”, Nature, Lond., 178, 491492.CrossRefGoogle ScholarPubMed
Lindahl, P. E., 1958. “Separation of Bull Spermatozoa Carrying X- and Y-chromosomes by Counter-streaming Centrifugation”, Ada Agric. Scand., 8, 226230.CrossRefGoogle Scholar
Mann, T., 1954. The Biochemistry of Semen. Methuen, London.CrossRefGoogle Scholar
May, J. M., 1952. “Extended and Corrected Tables of the Upper Percentage Points of the ‘Studentized’ Range”, Biometrika, 39, 192193.Google Scholar
Snedecor, G. W., 1956. Statistical Methods. 5th Ed. Iowa State College Press.Google Scholar
Snell, G. D., 1944. “Antigenic Differences between the Sperm of Different Inbred Strains of Mice”, Science, 100, 272273.CrossRefGoogle ScholarPubMed
Snell, G. D., and Poucher, H., 1943. “Relation of Number of Injections to the Titer of Sperm Iso-agglutins in Mice”, Proc. Soc. Exp. Biol. Med., 54, 261263.CrossRefGoogle Scholar
Zeleny, C. and Faust, E. C, 1915. “Size Dimorphism in the Spermatozoa from Single Testes”, J. Exp. Zool, 18, 187240CrossRefGoogle Scholar