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Investigating renal function during lithium treatment

Published online by Cambridge University Press:  09 July 2009

Derek G. Waller  and
J. Guy Edwards
Derek G. Waller*
Affiliation:
Clinical Pharmacology Group, Southampton General HospitalDepartment of Psychiatry, Royal South Hants Hospital, Southampton
J. Guy Edwards
Affiliation:
Clinical Pharmacology Group, Southampton General HospitalDepartment of Psychiatry, Royal South Hants Hospital, Southampton
*
1Address for correspondence: Dr Derek G. Waller, Clinical Pharmacology Group, Centre Block, Level F, Southampton General Hospital, Tremona Road, Southampton SO9 4XY.
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Synopsis

The tests that have been used to assess glomerular and tubular function in patients receiving treatment with lithium have been reviewed. The advantages and disadvantages of these are discussed. The most useful tests are the creatinine clearance, which may be predicted from the serum creatinine using a formula or nomogram, and the measurement of urine osmolality, followed if necessary by assessment of the maximum urine concentrating ability after desamino cys-1–8-D arginine vasopressin.

Type
Research Article
Information
Psychological Medicine , Volume 15 , Issue 2 , May 1985 , pp. 369 - 375
Copyright
Copyright © Cambridge University Press 1985

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