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Plasma cortisol-binding capacity in mental illness

Published online by Cambridge University Press:  09 July 2009

David J. King
David J. King
Affiliation:
From the Department of Mental Health, The Queen's University of Belfast
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Synopsis

Plasma cortisol-binding capacity (CBC) was determined in 18 psychiatric patients, including 14 who had affective disorders, and 18 controls. Men with unipolar depressive illnesses had significantly lower CBC values than men with bipolar illnesses and male controls. No other significant differences in CBC values were found and it was concluded that elevated total plasma cortisol levels in affective disorder were probably associated with increased levels of unbound cortisol. The possibility that low CBC values may be a genetic marker for certain types of affective disorder requires further investigation. The effect of certain drugs on CBC was also investigated.

Type
Research Article
Information
Psychological Medicine , Volume 3 , Issue 1 , February 1973 , pp. 53 - 65
Copyright
Copyright © Cambridge University Press 1973

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