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Changes in genetic and environmental influences on disordered eating between early and late adolescence: a longitudinal twin study

Published online by Cambridge University Press:  02 July 2015

A. K. Fairweather-Schmidt  and
T. D. Wade
A. K. Fairweather-Schmidt*
Affiliation:
School of Psychology, Flinders University, Adelaide, South Australia, Australia
T. D. Wade
Affiliation:
School of Psychology, Flinders University, Adelaide, South Australia, Australia
*
* Address for correspondence: Dr A. K. Fairweather-Schmidt, Ph.D., School of Psychology, Flinders University, GPO Box 2100, Adelaide, South Australia, 5001, Australia. (Email: Kate.Fairweather-Schmidt@flinders.edu.au)
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Abstract

Background

We investigated the genetic and environmental contributions to disordered eating (DE) between early and late adolescence in order to determine whether different sources of heritability and environmental risk contributed to these peak times of emergence of eating disorders.

Method

Adolescent female twins from the Australian Twin Registry were interviewed over the telephone with the Eating Disorder Examination (EDE). Data were collected at 12–15 and 16–19 years (wave 1: N = 699, 351 pairs; wave 3: N = 499, 247 pairs). Assessments also involved self-report measures related to negative life events and weight-related peer teasing.

Results

Unstandardized estimates from the bivariate Cholesky decomposition model showed both genetic influences and non-shared environmental influences increased over adolescence, but shared environmental influences decreased. While non-shared environmental sources active at ages 12–15 years continued to contribute at 16–19 years, new sources of both additive genetic and non-shared environmental risk were introduced at ages 16–19 years. Weight-related peer teasing in early-mid adolescence predicted increases of DE in later adolescence, while negative life events did not.

Conclusions

Two-thirds of the heritable influence contributing to DE in late adolescence was unique to this age group. During late adolescence independent sources of genetic risk, as well as environmental influences are likely to be related in part to peer teasing, appear key antecedents in growth of DE.

Keywords

AdolescentsenvironmentalgeneticGlobal EDElongitudinaltwins
Type
Original Articles
Information
Psychological Medicine , Volume 45 , Issue 15 , November 2015 , pp. 3249 - 3258
Copyright
Copyright © Cambridge University Press 2015 

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References

Abebe, DS, Lien, L, von Soest, T (2012). The development of bulimic symptoms from adolescence to young adulthood in females and males: a population-based longitudinal cohort study. International Journal of Eating Disorders 45, 737–745.Google Scholar
Allen, KL, Crosby, RD, Oddy, WH, Byrne, SM (2013). Eating disorder symptom trajectories in adolescence: effect of time, participant sex, and early adolescent depressive symptoms. Journal of Eating Disorders 1, 1–14.Google Scholar
Berg, KC, Peterson, CB, Frazier, P, Crow, SJ (2011). Convergence scores on the interview and questionnaire versions of the Eating Disorder Examination: a meta-analytic review. Psychological Assessment 23, 714–724.Google Scholar
Berg, KC, Peterson, CB, Frazier, P, Crow, SJ (2012 a). Psychometric evaluation of the Eating Disorder Examination and the Eating Disorder Examination-Questionnaire: a systematic review of the literature. International Journal of Eating Disorders 45, 428–438.CrossRefGoogle ScholarPubMed
Berg, KC, Stiles-Shields, EC, Swanson, SA, Peterson, CB, Leobow, J, Le Grange, D (2012 b). Diagnostic concordance of the interview and questionnaire versions of the Eating Disorders Examination. International Journal of Eating Disorders 45, 850–855.Google Scholar
Bird, EL, Halliwell, E, Diedrichs, PC, Harcourts, D (2013). Happy Being Me in the UK: a controlled evaluation of a school-based body image intervention with pre-adolescent children. Body Image 10, 326–334.Google Scholar
Brown, BB, Eicher, SA, Petri, S (1986). The importance of peer group (‘crowd’) affiliation in adolescence. Journal of Adolescence 9, 73–96.Google Scholar
Bulik, CM, Sullivan, PF, Kendler, KS (1998). Heritability of binge-eating and bulimia nervosa. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 81, 493–298.Google Scholar
Bulik, CM, Sullivan, PF, Wade, TD, Kendler, RC (2000) Twin studies of eating disorders: a review. International Journal of Eating Disorders 27, 1–20.Google Scholar
Culbert, KM, Burt, SA, McGue, M, Iacono, WG, Klump, KL (2009). Puberty and the genetic diathesis of disordered eating attitudes and behaviours. Journal of Abnormal Psychology 118, 788–796.Google Scholar
Eaves, LJ, Eysenck, HJ, Martin, NG, Jardine, R, Heath, AC, Feingold, L, Young, PA, Kendler, KS (1989). Genes, Culture and Personality: An Empirical Approach. Oxford University Press: London.Google Scholar
Edwards, B (2012). Growing up in Australia: The Longitudinal Study of Australian Children. The first decade of life. Family Matters 91, 7–17.Google Scholar
Edwards, B (2014). Growing up in Australia: The Longitudinal Study of Australian Children. Entering adolescence and becoming a young adult. Family Matters 95, 1–14.Google Scholar
Fairburn, CG, Cooper, Z (1993). The eating disorder examination. In Binge Eating: Nature, Assessment and Treatment (ed. Fairburn, C. G. and Wilson, G.T.), pp. 317–360. Guilford Press: New York.Google Scholar
Fairburn, CG, Cooper, Z, Doll, HA, O'Connor, ME, Bohn, K, Hawker, DM, Wales, JA, Palmer, RL (2009). Transdiagnostic cognitive-behavioral therapy for patients with eating disorders: a two-site trial with 60-week follow-up. American Journal of Psychiatry 166, 311–319.CrossRefGoogle ScholarPubMed
Fairburn, CG, Cooper, Z, Doll, HA, Welch, SL (1999). Risk factors for anorexia nervosa. Archives General Psychiatry 56, 468–476.Google Scholar
Fairburn, CG, Harrison, PJ (2003). Eating disorders. Lancet 361, 407–416.Google Scholar
Farish, S (2004). Funding arrangements for non-government schools 2005–2008: Recalculation of the modified Socioeconomic Status (SES) Indicator Using 2001 Australian Bureau of Statistics Census Data.Google Scholar
Favaro, A, Caregaro, L, Tenconi, E, Bosello, R, Santonastaso, P (2009). Time trends in age of onset of anorexia nervosa and bulimia nervosa. Journal of Clinical Psychiatry 70, 1715–1721.CrossRefGoogle ScholarPubMed
Garn, SM, LaVelle, M, Rosenberg, KR, Hawthorne, VM (1986). Maturational timing as a factor in female fatness and obesity. American Journal of Clinical Nutrition 43, 879–883.Google Scholar
Garner, DM, Olmstead, MP, Polivy, J (1983) Development and validation of a multi-dimensional eating disorder inventory for anorexia nervosa and bulimia. International Journal of Eating Disorders 2, 15–34.Google Scholar
Gray, M, Sanson, A (2005). Growing up in Australia: The Longitudinal Study of Australian Children. Family Matters 72, 4–9.Google Scholar
Gray, M, Smart, D (2008). Growing up in Australia: The Longitudinal Study of Australian Children is now walking and talking. Family Matters 79, 5–13.Google Scholar
Haines, J, Neumark-Sztainer, D, Eisenberg, ME, Hannan, PJ (2006). Weight teasing and disordered eating behaviors in adolescents: longitudinal findings from Project EAT (Eating Among Teens). Pediatrics 117, e209–215.Google Scholar
Hudson, JI, Hiripi, E, Pope, HGJ, Kessler, RC (2009). The prevalence and correlates of eating disorders in the National Comorbidity Survey Replication. Biological Psychiatry 61, 348–358.CrossRefGoogle Scholar
Kendler, KS, Neale, MC, Kessler, RC, Heath, AC, Eaves, LJ (1992). Childhood parental loss and adult psychopathology in women. A twin study perspective. Archives of General Psychiatry 49, 109–116.Google Scholar
Kessler, RC, Berglund, PA, Chiu, WT, Deitz, AC, Hudson, JI, Shahly, V, Aguilar-Gaxiola, S, Alonso, J, Angermeyer, MC, Benjet, C, Bruffaerts, R, de Girolamo, G, de Graaf, R, Maria Haro, J, Kovess-Masfety, V, O'Neill, S, Posada-Villa, J, Sasu, C, Scott, K, Viana, MC, Xavier, M (2013). The prevalence and correlates of binge eating disorder in the World Health Organization World Mental Health Surveys. Biological Psychiatry 73, 904–914.Google Scholar
Kotler, LA, Cohen, P, Davies, M, Pine, DS, Walsh, BT (2001) Longitudinal relationships between childhood, adolescent, and adult eating disorders. Journal of American Academy of Child and Adolescent Psychiatry 40, 1434–1440.Google Scholar
Klump, KL (2013) Puberty as a critical risk period for eating disorders: a review of human and animal studies. Hormones and Behavior 64, 399–410.Google Scholar
Klump, KL, Burt, SA, McGue, M, Iacono, WG (2007). Changes in genetic and environmental influences on disordered eating across adolescence: a longitudinal twin study. Archives of General Psychiatry 64, 1409–1415.Google Scholar
Klump, KL, Culbert, KM, Slane, JD, Burt, SA, Sisk, CL, Nigg, JT (2012). The effects of puberty on genetic risk for disordered eating: evidence for a sex difference. Psychological Medicine 42, 627–637.Google Scholar
Klump, KL, Kaye, WH, Strober, M (2001). The evolving genetic foundations of eating disorders. Psychiatric Clinics of North America 24, 215–225.CrossRefGoogle ScholarPubMed
Klump, KL, McGue, M, Iacono, WG (2003). Differential heritability of eating attitudes and behaviors in prepubertal versus pubertal twins. International Journal of Eating Disorders 33, 287–292.CrossRefGoogle ScholarPubMed
Larsen, RW, Maryse, HR, Moneta, G, Holmbeck, G, Duckett, E (1996). Changes in adolescents’ daily interactions with their family from ages 10–18: disengagement and transformation. Developmental Psychology 32, 744–754.CrossRefGoogle Scholar
le Grange, D, Crosby, RD, Rathouz, PJ, Leventhal, BL (2007). A randomised controlled comparison of family-based treatment and supportive psychotherapy for adolescent bulimia nervosa. Archives of General Psychiatry 64, 1049–1056.Google Scholar
Lewinsohn, PM, Striegel-Moore, RH, Seeley, JR (2000). Epidemiology and natural course of eating disorders in young women from adolescence to young adulthood. Journal of the Academy of Child Adolescent Psychiatry 39, 1284–1292.Google Scholar
Lock, J, Le Grange, D, Agras, WS, Moye, A, Bryson, SW, Booil, J (2010). Randomized clinical trial comparing family-based treatment with adolescent-focused individual therapy for adolescents with anorexia Nervosa. Archives of General Psychiatry 67, 1025–1032.Google Scholar
Little, RJA, Rubin, DB (1987). Statistical Analysis with Missing Data. Wiley: New York, NY.Google Scholar
McKnight Investigators (2003). Risk factors for the onset of eating dis- orders in adolescent girls: results of the McKnight longitudinal risk factor study. American Journal of Psychiatry 160, 248–254.CrossRefGoogle Scholar
Neale, BM, Mazzeo, SE, Bulik, CM (2003). A twin study of dietary restraint, disinhibition, and hunger. Twin Research 6, 471–478.Google Scholar
Neale, MC (1994). Mx: Statistical Modeling, 3rd edn. Department of Psychiatry, VA Commonwealth University: Richmond, VA.Google Scholar
Neumark-Sztainer, D, Wall, M, Larson, NI, Eisenberg, ME, Loth, K (2011). Dieting and disordered eating behaviors from adolescence to young adulthood: finding from a 10-year longitudinal study. Journal of the American Dietetic Association 111, 1004–1011.Google Scholar
Plomin, R, DeFries, JC, McClearn, GE (1990). Behavioral Genetics: A Primer, 2nd edn. Freeman Company: New York, NY.Google Scholar
Richardson, SM, Paxton, SJ (2010). An evaluation of a body image intervention based on risk factors for body dissatisfaction: a controlled study with adolescent girls. International Journal of Eating Disorders 43, 112–122.Google Scholar
Simon, J, Schmidt, U, Pilling, S (2005). The health service use and cost of eating disorders. Psychological Medicine 35, 1543–1551.Google Scholar
Stice, E, Marti, NC, Rohde, P (2013). Prevalence, incidence, impairment, and course of the proposed DSM-5 eating disorder diagnoses in an 8-year prospective community study of young women. Journal of Abnormal Psychology 122, 445–457.Google Scholar
Sullivan, PF, Eaves, LJ (2002). Evaluation of analyses of univariate discrete twin data. Behavior Genetics 32, 221–227.Google Scholar
Tozzi, F, Sullivan, PF, Fear, JL, McKenzie, J, Bulik, CM (2003) Causes and recovery in anorexia nervosa: the patient's perspective. International Journal of Eating Disorders 33, 143–154.Google Scholar
Wade, TD, Bergin, JL, Tiggemann, M, Bulik, CM, Fairburn, CG (2006). Prevalence and long term course of lifetime eating disorders in an adult Australian twin cohort. Australian and New Zealand Journal of Psychiatry 40, 121–128.Google Scholar
Wade, TD, Byrne, S, Bryant-Waugh, R (2008). The eating disorder examination: norms and construct validity with young and middle adolescent girls. International Journal of Eating Disorders 41, 551–558.Google Scholar
Wade, TD, Gillespie, N, Martin, NG (2007). A comparison of early family life events amongst monozygotic twin women with lifetime anorexia nervosa, bulimia nervosa, or major depression. International Journal of Eating Disorders 40, 679–686.Google Scholar
Wade, TD, Hansell, NK, Crosby, RD, Bryant-Waugh, R, Treasure, J, Nixon, R, Byrne, S, Martin, NG (2013). A Study of Changes in Genetic and Environmental Influences on Weight and Shape Concern across Adolescence. Journal of Abnormal Psychology 122, 119–130.CrossRefGoogle ScholarPubMed
Wade, TD, Treasure, J, Schmidt, U (2011). A case series evaluation of the Maudsley Model for treatment of adults with anorexia nervosa. European Eating Disorders Review 19, 382–389.Google Scholar
Wade, TD, Wilksch, SM, Lee, C (2012). A longitudinal investigation of the impact of disordered eating on young women's quality of life. Health Psychology 31, 352–359.Google Scholar
Welch, SL, Doll, HA, Fairburn, CG (1997). Life events and the onset of bulimia nervosa: a controlled study. Psychological Medicine 27, 515–522.Google Scholar
Wilksch, SM, Paxton, SJ, Byrne, SM, Austin, SB, McLean, SA, Thompson, KM, Dorairaj, K, Wade, TD (2015). Prevention across the spectrum: a randomized-controlled trial of three programs to reduce risk factors for both eating disorders and obesity. Psychological Medicine 45, 1811–1823.Google Scholar
Wilksch, SM, Wade, TD (2009). An investigation of temperament endophenotype candidates for early emergence of the core cognitive component of eating disorders. Psychological Medicine 39, 811–821.CrossRefGoogle ScholarPubMed
Wilksch, SM, Wade, TD (2010). Risk factors for clinically significant importance of shape and weight in adolescent girls. Journal Abnormal Psychology 119, 206–215.Google Scholar