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Methysergide in mania: a double-blind comparison with thioridazine
Published online by Cambridge University Press: 09 July 2009
Synopsis
During 20 separate illnesses 17 severely disturbed manic patients were given either methysergide or thioridazine in a 21 day double-blind controlled trial. For most of the trial patients received either 9 mg methysergide or 450 mg thioridazine daily; during one 24-hour period 12 mg methysergide or 600 mg thioridazine was administered. Daily clinical assessments were made. Methysergide proved significantly less effective than the phenothiazine.
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- Copyright © Cambridge University Press 1972
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