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Aging changes in the central nervous system

Published online by Cambridge University Press:  17 November 2008

Margaret M Esiri
Margaret M Esiri*
Affiliation:
Departments of Neuropathology and Clinical Neurology, Radcliffe Infirmary, Oxford, UK
*
Margaret M Esiri, Clinical Reader in Neuropathology, Departments of Neuropathology and Clinical Neurology, Radcliffe Infirmary, Oxford, UK.
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Abstract

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Type
Biological gerontology
Information
Reviews in Clinical Gerontology , Volume 1 , Issue 2 , May 1991 , pp. 113 - 118
Copyright
Copyright © Cambridge University Press 1991

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References

1Ulrich, J ed. Histology and histopathology of the ageing brain (Interdisciplinary topics in gerontology, volume 25). Basel: Karger, 1988.Google Scholar
2Alzheimer, A. Über eine eigenartige Erkrankung der Hirnrinde. Allg Psychiat 1907; 64: 146–48.Google Scholar
3Dayan, AD. Quantitative histological studies on the aged human brain. 1. Senile plaques and neurofibrillary tangles in ‘normal’ patients. Acta Neuropathol [Berl] 1970; 16: 85–95.Google Scholar
4Tomlinson, BE, Blessed, G, Roth, M. Observations on the brains of non-demented old people. J Neurol Sci 1968; 7: 331–56.CrossRefGoogle ScholarPubMed
5Tomlinson, BE, Corsellis, JAN. Ageing and the dementias. In: Adams, JH, Corsellis, JAN, Duchen, LW eds. Greenfield's neuropathology, fourth edition. London: Edward Arnold 1984: 951–1024.Google Scholar
6Terry, RD, Hansen, LA, De Teresa, R, Davies, P, Tobias, H, Katzman, R. Senile dementia of the Alzheimer type without neocortical neurofibrillary tangles. J Neuropathol Exp Neurol 1987; 46: 262–68.Google Scholar
7Khatchaturian, LS. Diagnosis of Alzheimer's disease. Arch Neurol 1985; 42: 1097–1104.Google Scholar
8Lamy, C, Duykaerts, G, Delaere, P et al. Comparison of seven staining methods for senile plaques and neurofibrillary tangles in a prospective series of 15 elderly patients. Neuropathol Appl Neurobiol 1989; 15: 563–78.CrossRefGoogle Scholar
9Allsop, D, Haga, S-I, Haga, C, Ikeda, S-I, Mann, DMA, Ishi, T. Early senile plaques in Down's syndrome brains show a close relationship with cell bodies of neurons. Neuropathol Appl Neurobiol 1989; 15: 531–42.CrossRefGoogle ScholarPubMed
10Davies, L, Wolska, B, Hilbich, C et al. A4 amyloid protein deposition and the diagnosis of Alzheimer's disease. Neurology 1988; 38: 1688–93.CrossRefGoogle ScholarPubMed
11Ball, MJ, Griffin-Brookes, S, Macgregor, J, Nagy, B, Ojalvo-Rose, E, Fewster, PH. Neuropathological definition of Alzheimer's disease: multivariate analyses in the morphometric distinction between Alzheimer's dementia and normal ageing. Alz Dis Assoc Dis 1988; 2: 29–37.CrossRefGoogle Scholar
12Tiemey, MG, Fisher, RH, Lewis, AJ et al. The NINCDSADRDA work group criteria for the clinical diagnosis of probable Alzheimer's disease: a clinicopathological study of 57 cases. Neurology 1988; 38: 359–64.Google Scholar
13Herzog, AG, Kemper, TL. Amygdaloid changes in ageing and dementia. Arch Neurol 1980; 37: 625–29.CrossRefGoogle Scholar
14Walton, S. Clinical observations of impaired cranial nerve function in senile dementia. Acta Psychiatr Scand 1974; 50: 539–47.CrossRefGoogle Scholar
15Harrison, PJ, Pearson, RCH. Olfaction and psychiatry. Br J Psychiatry 1989; 155: 822–28.CrossRefGoogle ScholarPubMed
16Esiri, MM, Wilcock, GK. The olfactory bulbs in Alzheimer's disease. J Neurol Neurosurg Psychiatry 1984; 47: 56–60.CrossRefGoogle ScholarPubMed
17Ohm, TG, Braak, H. Olfactory bulb changes in Alzheimer's disease. Acta Neuropathol (Berl) 1987; 73: 365–69.Google Scholar
18Talamo, BR, Rudel, RA, Kosik, KA et al. Pathological changes in olfactory neurons in patients with Alzheimer's disease. Nature 1989; 337: 736–39.CrossRefGoogle ScholarPubMed
19Pearson, RCA, Powell, TPS. The neuroanatomy of Alzheimer's disease. Rev Neurosci 1989; 2: 101–22.CrossRefGoogle ScholarPubMed
20Mann, DMA, Yates, PO, Marcyniuk, B, Ravindra, CR. The topography of plaques and tangles in Down's syndrome patients of different ages. Neuropathol Appl Neurobiol 1986; 12: 447–57.Google Scholar
21Roberts, E. Alzheimer's disease may begin in the nose and may be caused by aluminosilicates. Neurobiol Aging 1986; 7: 561–67.CrossRefGoogle ScholarPubMed
22Esiri, MM, Pearson, RCA, Steele, JE, Bowen, DM, Powell, TPS. A quantitative study of the neurofibrillary tangles and the choline acetyltransferase activity in the cerebral cortex and the amygdala in Alzheimer's disease. J Neurol Neurosurg Psychiatry 1990; 53: 161–65.CrossRefGoogle ScholarPubMed
23Anderton, BH, Brion, JP. Ultrastructural and biochemical basis of Alzheimer's disease. Reviews in Clinical Gerontology 1990; 1: 17–28.CrossRefGoogle Scholar
24Eikelenboom, P, Hack, CE, Rosemuller, JM, Stam, FC. Complement activation in amyloid plaques in Alzheimer's dementia. Virchows Arch [B] 1989; 56: 259–62.CrossRefGoogle ScholarPubMed
25Hyman, BT, Van Hoesen, GW, Kromer, LJ, Damasio, AR. Perforant pathway changes and the memory impairment of Alzheimer's disease. Ann Neurol 1986; 20: 4742–51.CrossRefGoogle ScholarPubMed
26McKee, AC, Kowall, NW, Kosik, KS. Microtubular reorganisation and dendrite growth response in Alzheimer's disease. Ann Neurol 1989; 26: 652–59.CrossRefGoogle Scholar
27Oliver, C, Holland, AJ. Down's syndrome and Alzheimer's disease – a review. Psychol Med 1986; 16: 307–22.CrossRefGoogle ScholarPubMed
28Tanzi, RE, St George-Hyslop, PH, Gusella, JF. Molecular genetic approaches to Alzheimer's disease. Trends Neurosci 1989; 12: 152–58.CrossRefGoogle ScholarPubMed
29Rumble, B, Retallack, R, Hillbich, C et al. Amyloid A4 protein and its precursor in Down's syndrome and Alzheimer's disease. N Engl J Med 1989; 320:1446–52.CrossRefGoogle ScholarPubMed
30Lee, S-S, Stemmermann, GN. Congophilic angiopathy and cerebral haemorrhage. Arch Pathol Lab Med 1978; 102: 317–21.Google Scholar
31Rosemuller, JM, Eikelenboom, P, Stam, FC, Beyreuther, K, Masters, CL. A4 protein in Alzheimer's disease: primary and secondary cellular events in extracellular amyloid deposition. J Neuropathol Exp Neurol 1989; 48: 674–91.Google Scholar
32Joachim, CL, Mori, H, Selkoe, DJ. Beta amyloid protein deposition in tissues other than brain in Alzheimer's disease. Nature 1989; 341: 226–30.Google Scholar
33Palmert, MR, Podlisny, MB, Witker, DS et al. The beta amyloid protein precursor of Alzheimer's disease has soluble derivatives found in human brain and cerebrospinal fluid. Proc Natl Acad Sci USA 1989; 86: 6338–42.CrossRefGoogle ScholarPubMed
34Wolozin, B, Davies, P. Alzheimer-related neuronal protein A68; specificity and distribution. Ann Neurol 1987; 22: 521–26.Google Scholar