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Lithium Therapy in Aggressive Mentally Subnormal Patients

Published online by Cambridge University Press:  29 January 2018

P. G. Dale
P. G. Dale*
Affiliation:
Coldeast Hospital, Sarisbury Green, Southampton
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Summary

In a series of fifteen aggressive mentally subnormal patients treated with lithium carbonate, there was an improvement in aggressive behaviour in eleven cases, three patients showed no change and one patient became worse during lithium treatment. The response to lithium therapy was assessed by clinical observation and retrospective analysis of daily ward reports. Treatment had to be discontinued in one patient who developed tardive dyskinesia, but otherwise side effects were not a problem.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 137 , Issue 5 , November 1980 , pp. 469 - 474
Copyright
Copyright © Royal College of Psychiatrists, 1980 

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References

Campbell, M., Fish, B., Korein, J., Shapiro, T., Collins, P. & Koh, C. (1972) Lithium and chlorpromazine: a controlled crossover study of hyperative severely disturbed young children. Journal of Autism and Childhood Schizophrenia, 2, 234–63.Google Scholar
Cooper, A. F. & Fowlie, H. C. (1973) Control of gross self-mutilation with lithium carbonate. British Journal of Psychiatry, 122, 370–1.CrossRefGoogle ScholarPubMed
Dostal, T. & Zvolsky, P. (1970) Anti-aggressive effect of lithium salts in severe mentally retarded adolescents. International Pharmacopsychiatry, 5, 203–7.Google Scholar
Forssman, H. & Walinder, J. (1969) Lithium treatment on atypical indication. Acta Psychiatrica Scandinavica, Supplement 207, 34–40.Google Scholar
Goetzl, U., Grunberg, G. & Berkowitz, B. (1977) Lithium carbonate in the management of hyperactive aggressive behaviour of the mentally retarded. Comprehensive Psychiatry, 18, 599–606.Google Scholar
Gram, L. F. & Rafaelsen, O. J. (1972) Lithium treatment of psychotic children and adolescents. A controlled clinical trial. Acta Psychiatrica Scandinavica, 48, 253–60.CrossRefGoogle ScholarPubMed
Lion, J. R., Hill, J. & Madden, D. J. (1975) Lithium carbonate and aggression: a case report. Diseases of the Nervous System, 36, 97–8.Google ScholarPubMed
Micev, V. & Lynch, D. M. (1974) Effect of lithium in disturbed severely mentally retarded patients. British Journal of Psychiatry, 125, 110.Google Scholar
Morrison, S. D., Erwin, C. W., Gianturco, C. T. & Gerber, C. J. (1973) Effect of lithium on combative behaviour in humans. Diseases of the Nervous System, 34, 186–9.Google ScholarPubMed
Shader, R. I., Jackson, A. H. & Dodes, L. M. (1974) The anti-aggressive effects of lithium in man. Psychopharmacologia (Berlin), 40, 17–24.Google Scholar
Sheard, M. H. (1971) Effect of lithium on human aggression. Mature, 230, 113–4.CrossRefGoogle ScholarPubMed
Sheard, M. H. (1975) Lithium in the treatment of aggression. The Journal of Nervous and Mental Disease, 160, No. 2, 108–18.Google Scholar
Sheard, M. H., Marini, J. L., Bridges, C. I. & Wagner, E. (1976) The effect of lithium on impulsive aggressive behaviour in man. American Journal of Psychiatry, 133, 1409–13.Google Scholar
Tupin, J. P., Smith, D. B., Clanon, T. L., Km, L. I., Nugent, A. & Groupe, A. (1973) The long-term use of lithium in aggressive prisoners. Comprehensive Psychiatry, 14, 311–7.CrossRefGoogle ScholarPubMed
Worrall, E. P., Moody, J. P. & Naylor, G. J. (1975) Lithium in non-manic depressives: anti-aggressive effect and red blood cell lithium values. British Journal of Psychiatry, 126, 464–8.CrossRefGoogle Scholar
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