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Can Buspirone Induce Rebound, Dependence or Abuse?

Published online by Cambridge University Press:  06 August 2018

Malcolm Lader
Malcolm Lader*
Affiliation:
Institute of Psychiatry, De Crespigny Park, London SE5 8AF
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Abstract

Buspirone is a newer anxiolytic which differs chemically and pharmacologically from the benzodiazepines. The question as to whether buspirone can induce rebound, dependence, or abuse can be examined through a variety of clinical and control studies, as well as animal studies, together with meticulous follow-up of adverse reports. It is concluded that, on present evidence, the short-term use of buspirone is unlikely to be followed by rebound or long-term use through dependence; nor is abuse likely to be a problem.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 159 , Issue S12: Anxiety and Serotonin , September 1991 , pp. 45 - 51
Copyright
Copyright © The Royal College of Psychiatrists 

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