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The Dysphoric Syndrome in Schizophrenia and its Implications for Relapse

Published online by Cambridge University Press:  06 August 2018

Steven R. Hirsch  and
Anthony G. Jolley
Steven R. Hirsch
Affiliation:
Department of Psychiatry, Charing Cross and Westminster Medical School, London
Anthony G. Jolley
Affiliation:
Department of Psychiatry, Charing Cross and Westminster Medical School, London
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Extract

The presence of non-psychotic neurotic and dysphoric symptoms in schizophrenia has been recognised from the days of Bleuler (1908) and Kraepelin (1896) and is inherent in the hierarchical schema explicated by Foulds (1976) and commonly employed by psychiatrists in the diagnosis of psychotic disorder. Of such symptoms, those which may be characterised as depressive in nature have been the focus of much recent interest in view of claims that they may be iatrogenic. That such symptoms occur widely in schizophrenia is beyond dispute, but their relationship to the process of the illness and its treatment remains a subject of contention.

Type
II. From the Perspective of Neurobiology and Pharmacotherapy
Information
The British Journal of Psychiatry , Volume 155 , Issue S5: Schizophrenia as a Systems Disorder: The Relevance of Mediating Processes for Theory and Therapy , July 1989 , pp. 46 - 50
Copyright
Copyright © The Royal College of Psychiatrists 

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References

American Psychiatric Association (1980) Diagnostic and Statistical Manual of Mental Disorders (3rd edn). Washington: APA.Google Scholar
Ananth, J. & Ghadirian, A. M. (1980) Drug-induced mood disorders. International Pharmacopsychiatry, 15, 59–73.Google Scholar
Bleuler, E. (1908) Die Prognose der Dementia Praecox Schizophreniegruppe. Allgemeine Zeitschrift für Psychiatrie, 65, 436–464. Reprinted (1987) in The Clinical Roots of Schizophrenia (eds J. Cutting & M. Shepherd). London: Cambridge University Press.Google Scholar
Carpenter, W. T., Stephens, W. T., Rey, A., et al (1982) Early intervention versus continuous pharmacotherapy in schizophrenia. Psychopharmacology Bulletin, 18, 21–23.Google Scholar
Derogatis, L. R., Lipman, R. S. & Covi, L. (1973) An outpatient psychotic rating scale (SCL-90). Preliminary report. Psychopharmacology Bulletin, 9, 13–28.Google Scholar
Foulds, G. W. (1976) The Hierarchical Nature of Personal Illness. London: Academic Press.Google Scholar
Galdi, J., Kelly, J. T., Rieder, R. O., et al (1985) The role of genetic factors in the induction of extrapyramidal side-effects in schizophrenic patients. In Psychiatry. The State of the Art (eds P. Pichot, P. Berner, R. Wolf, et al). New York: Plenum.Google Scholar
Herz, M. I. & Melville, C. (1980) Relapse in schizophrenia. American Journal of Psychiatry, 137, 801–805.Google Scholar
Herz, M. I., Symanski, H. V. & Simon, J. C. (1982) Intermittent medication for stable schizophrenic outpatients: An alternative to maintenance medication. American Journal of Psychiatry, 139, 918–922.Google Scholar
Hirsch, S. R. (1982) Depression “revealed” in schizophrenia. British Journal of Psychiatry, 140, 421–423.CrossRefGoogle Scholar
Hirsch, S. R., Gaind, R., Rohde, P. D., et al (1973) Outpatient maintenance of chronic schizophrenic patients with long-acting fluphenazine: A double-blind placebo trial. British Medical Journal, i, 633–637.Google Scholar
Hirsch, S. R., Jolley, A. G., Manchanda, R., et al (1987) Early intervention medication as an alternative to continuous depot treatment in schizophrenia. Preliminary report. In Psychosocial Treatment of Schizophrenia (eds Strauss, J., Böker, W. & Brenner, H. D.). Bern: Huber.Google Scholar
Johnson, D. A. W. (1981) Studies of depressive symptoms in schizophrenia. British Journal of Psychiatry, 139, 89–101.Google Scholar
Kane, J. M., Rifkin, A., Woerner, M., et al (1983) Low-dose neuroleptic treatment of outpatient schizophrenics. I. Preliminary results for relapse rates. Archives of General Psychiatry, 40, 893–896.Google Scholar
Knights, A. & Hirsch, S. R. (1981) “Revealed” depression and drug treatment of schizophrenia. Archives of General Psychiatry, 38, 806–811.Google Scholar
Kraepelin, E. (1896) Psychiatrie (5th edn). Leipzig. Reprinted (1987) in The Clinical Roots of Psychiatry (eds Cutting, J. & Shepherd, M.). London: Cambridge University Press.Google Scholar
Moeller, H. J. & Von Zerssen, D. (1981) Depressive Symptomatik im stationären Behandlungsverlauf von 280 schizophrenen Patienten. Pharmacopsychiatria, 14, 172–179.Google Scholar
Pietzcker, A., Gaebel, W., Koepcke, W., et al (1986) A German multicenter study of the neuroleptic long-term therapy of schizophrenic patients. Preliminary report. Pharmacopsychiatry, 19, 161–166.Google Scholar
Van Putten, T. & Marder, S. (1985) The dysphoric syndrome and its relation to EPS. In Psychiatry: The State of the Art (eds P. Pichot, P. Berner, R. Wolf, et al). New York: Plenum.Google Scholar
Van Putten, T. & May, P. R. A. (1978) “Akinetic’ depression in schizophrenia. Archives of General Psychiatry, 35, 1101–1107.CrossRefGoogle ScholarPubMed
Wing, J. K., Cooper, J. E. & Sartorius, N. (1974) The Measurement and Classification of Psychiatric Symptoms. London: Cambridge University Press.Google Scholar
Wistedt, B. & Palmstierna, T. (1983) Depressive symptoms in chronic schizophrenic patients after withdrawal of long-acting neuroleptics. Journal of Clinical Psychiatry, 44, 369–371.Google Scholar
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